Primary chondrosarcoma of the heart

Abstract

Primary cardiac chondrosarcoma is extremely rare with very few cases reported in the literature. Most cardiac chondrosarcomas described in the literature are secondary. We report herein a case of 22-year-old man who presented with easy fatigability, which the general practitioner diagnosed as mitral stenosis clinically. Echocardiography showed left atrial mass, possibly myxoma. The histopathology of the excised mass revealed mesenchymal chondrosarcoma, confirmed by immunohistochemistry. Clinical and radiological studies did not reveal any other neoplasm. #

A fatal case of primary cardiac chondrosarcoma presenting with amaurosis fugax

“…Furthermore, it provides better soft tissue contrast than echocardiography, and can also depict calcification and haemorrhagic areas within tumours 11. MRI better defines the extension of tumours into the interatrial septum and pulmonary veins, as well as into the pericardium 11. In the present case, transthoracic echocardiography was used initially, followed by transoesophageal echocardiography for better representation of the left atrium and more accurate preoperative assessment of the tumour due to its superior spatial resolution.…”

“…However, a CT scan can more accurately image the heart as well as the surrounding mediastinum. Furthermore, it provides better soft tissue contrast than echocardiography, and can also depict calcification and haemorrhagic areas within tumours 11. MRI better defines the extension of tumours into the interatrial septum and pulmonary veins, as well as into the pericardium 11.…”

“…Regarding the management of PCC, surgery remains the first-line treatment; however, long-term survival after surgical excision is poor due to infiltrative growth with following early local recurrence and metastases 11. Surgery is recommended not only to obtain a tissue diagnosis but also to relieve tumour compression with subsequent prolonged survival and improved quality of life 10…”

“…The prognosis of PCC is extremely poor and limited to weeks or months 6 7 11. Surgical and chemotherapeutic strategies have both generally been disappointing for most patients.…”

Radiofrequency ablation of metastatic chondrosarcoma-associated refractory ventricular tachycardia originating from the right ventricular outflow tract: A case report and literature review

“…The present case was determined to be a mesenchymal chondrosarcoma as confirmed by pathological examination. ESMC may appear in any location that contains mesenchymal cells; primary sites include limb extremities, the torso, the head and neck, and rarely the heart (23)(24)(25). Compared with the myxoid subtype, the ESMC subtype is rare, more aggressive and with poor prognosis due to the high probability of metastases (26), which may occur several years following the initial treatment.…”