Primary Cardiac Lymphoma

Abstract

p r i m a r y cardiac lymphoma; echocardiography Case Report A previously healthy 85-year-old woman pre-Address for correspondence and reprint requests: Dennis Center, 759 Chestnut Street, Springfield, MA 01199. Fax: 413-794-0198. nificant respiratory variation. The junction of was also spared. The pacing wires were free of A. Tighe, M.D., Division of Cardiology, Baystate Medical the superior vena cava with the right atrium

Primary cardiac lymphoma

“…In this regard, a small rising in alkaline phosphatase, aspartame aminotransferase, alanine aminotransferase [2,8,22,46], and total bilirubin have been reported [2,46]. Anemia [21,35] and thrombocytopenia [14,38] have also been shown in some cases. An elevated serum concentration of soluble interleukin-2 receptor (sILR) has been found in some cases [6,26,48].…”

“…Moreover, TEE could be the method of choice for detecting masses localized within the left atrial appendage and the superior vena cava [52]. TEE has shown intracardiac mass in several cases [2,14,19,23,31,36,39,42,47,51,53], mainly when the TTE failed to show the heart tumor [37,38,46]. …”

“…However, TTE may miss mass lesions [17,32,38] while showing only a concurrent pericardial effusion [8,[10][11][12]18,21,26,49,51], or just a pericardial thickening [29], or may show the tumor in a more advanced stage [5]. Severe diastolic dysfunction has been reported by Tanaka et al in a 72-year-old woman with PCL [26].…”

“…ECG changes are summarized in Table 2. Complete AVblock is the ECG change which is most frequently observed in patients with PCL [12,18,[38][39][40][41]. This electrocardiographic abnormality can be unmasked by noncardiac surgery [18].…”

A Case of Primary Cardiac Lymphoma: Analysis of the Role of Echocardiography in Early Diagnosis

“…We evaluated all reported cases of PCL between 1989 and 2005 in which the lymphoma was strictly confined to the heart and/or pericardium and those cases with a single, asymptomatic extracardiac foci of disease. According to these criteria 78 cases were reported, male to female ratio was 3:2 and the mean age at presentation was 63 years (range 8–90 years) 2–20 . In 52% of cases the disease was limited to a single focus within the heart/pericardium and in 48% there were multiple foci of disease.…”