Primary carcinoma of the nail bed

Periungual basal cell carcinoma: A case report with review of literature

“…Presentation varies from onycholysis[610] to longitudinal melanonychia,[1217] and the most common sign of the disease is ulceration[78141618202124–26] around and of the nail plate, as seen in our subject.…”

“…Male: female ratio was 1.8:1. The thumb was the most frequently affected site[568912131519242628] and the hallux was reported in five cases. [1118212227] The right middle finger was involved in three cases[41620] and both hands were affected with almost similar frequency.…”

Periungual Basal Cell Carcinoma: Case Report and Literature Review

“…There was a slight predilection for men, with a male to female ratio of 1.6:1. Nail plate involvement was noted in 8 patients 2,3,5,6,8,13,16 ; the clinical presentations varied from longitudinal melanonychia, which mimicked melanoma in 2 patients, 8,13 to partial 16 or complete nail plate destruction, 6 to onycholysis with subungual debris, 2 to ulceration within the nail bed. 3 Seven individuals, including our patient, had tumor that either involved or was in proximity to the nailfold.…”

“…10,16 Amputation of the distal digit was performed for five tumors, 3,4,7,11,15 and curettage followed by application of salicylic acid and podophyllin was performed for one tumor. 2 One patient was referred for treatment and subsequently lost to follow-up. 9 In conclusion, the nail unit is an uncommon location for basal cell carcinoma.…”

“…1 To the best of our knowledge, basal cell carcinoma occurring in the nail unit has been reported in only 17 patients in the English literature. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] We present a man with basal cell carcinoma of the nail unit and review the literature regarding the unique presentation of this tumor. We also discuss the common diagnostic difficulties when managing nail unit basal cell carcinomas.…”