Primary carcinoma of the middle‐ear; Report of a case

Newhart, Horace

doi:10.1288/00005537-191707000-00002

Cited by 32 publications

(9 citation statements)

References 6 publications

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“…The peak age at presentation from previous reports has been between the fifth and sixth decades of life [1][2][3] . There has been no prior report of squamous cell carcinoma of the middle ear from Nigeria.…”

Section: Discussionmentioning

confidence: 99%

“…The relative frequency of chronic otitis media in two different studies of cancer of the middle ear cleft was reported to be 85% and 28% respectively, which strongly suggests a relationship between otitis media and aural cancer 2,3 . In a recent report, human papilloma virus types 16 and 18 have been associated with squamous cell carcinoma of the middle ear at both tissue and molecular levels, thus providing a good model to explain the pathogenesis of chronic inflammation-related human malignancies 4 .…”

Section: Introductionmentioning

confidence: 96%

“…Malignant tumours of the mastoid and middle ear as a groups are rare, accounting for 5 to 26% of all ear neoplasms [1][2][3] . Of these neoplasms, squamous cell carcinoma is the most common, with an ageadjusted incidence of 1 case in 1 million and peak age of 60 years [1][2][3] .…”

Section: Introductionmentioning

confidence: 99%

“…Of these neoplasms, squamous cell carcinoma is the most common, with an ageadjusted incidence of 1 case in 1 million and peak age of 60 years [1][2][3] .…”

Section: Introductionmentioning

confidence: 99%

“…The major etiological factor is chronic suppurative otitis media [1][2][3][4] although irradiation and inverted papilloma of the middle ear have also been reported to be additional risk factors 1,2,5 . The relative frequency of chronic otitis media in two different studies of cancer of the middle ear cleft was reported to be 85% and 28% respectively, which strongly suggests a relationship between otitis media and aural cancer 2,3 .…”

Section: Introductionmentioning

confidence: 99%

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Squamous cell carcinoma of the mastoid – a report of two cases

Lasisi

Ogunleye²,

Akang³

2006

Ghana Medical Journal

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SUMMARYMalignant tumours of the mastoid are rare, the majority being squamous cell carcinomas. We report two cases whose clinical presentation mimicked mastoid abscess with intracranial complications. The first case is a twenty year Nigerian lady who presented to the Emergency Room of the Otorhinolaryngology Department with a one month history of headache, low grade fever, left facial palsy, neck stiffness and left post-auricular swelling on a background of left chronic suppurative otitis media since childhood. An initial diagnosis of meningitis and mastoid abscess secondary to chronic suppurative otitis media was made but histology of the mastoid specimen revealed keratinizing squamous cell carcinoma, which was treated with palliative primary radiotherapy. The second case is a 45-year old man with a chronic mastoiditis and mastoid abscess that was later found to be suamous cell carcinoma of the mastoid and was managed with combination of surgery and radiotherapy. The report highlights advanced stage of the disease at presentation, and discusses the etiology and management. To the best of our knowledge, these are the first cases of this entity to be documented in Africans.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

“…Of these neoplasms, squamous cell carcinoma is the most common, with an ageadjusted incidence of 1 case in 1 million and peak age of 60 years [1][2][3] .…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Squamous cell carcinoma of the mastoid – a report of two cases

Lasisi

Ogunleye²,

Akang³

2006

Ghana Medical Journal

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Sarcoma of the Mastoid

White¹

1927

Archives of Otolaryngology - Head and Neck Surgery

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Neoplasms Involving the Middle Ear

Schall¹

1935

Archives of Otolaryngology - Head and Neck Surgery

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In no field of otology is there so much confusion as in the treatment of neoplasms of the middle ear. The general attitude has been that radical mastoidectomy should be performed but that the outlook is hopeless and the patient doomed.The literature is scanty. The older literature refers to malignant growths of the middle ear as medical curiosities. Newhart1 stated that he found reports of only 8 cases in the American literature. Keeler2 in 1922 thoroughly reviewed the literature and compiled 60 instances and added 2 of his own. Since 1922, Barnes,3 Furstenberg,4 Lewis,5 Burton6 and Fraser7 have presented reports of cases. INCIDENCEIn the past twelve years 15 patients with neoplasms involving the middle ear were seen by the otologic staff of the Massachusetts Eye and Ear Infirmary. Three of these patients are now living\p=m-\two, four and nine years, respectively, after treatment. In the same period 90,040 patients with pathologic conditions of the ear were seen at this hospital; so in this series the incidence was 1 in 6,000 cases of disease of the ear. This paper is based on personal experience in 6 cases\p=m-\2from the series of the Massachusetts Eye and Ear Infirmary, 3 from the Collis P. Huntington Memorial Hospital and 1 from private practice. They were equally divided between the sexes; all the patients were past 45.

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Primary carcinoma of the middle‐ear; Report of a case

Cited by 32 publications

References 6 publications

Squamous cell carcinoma of the mastoid – a report of two cases

Squamous cell carcinoma of the mastoid – a report of two cases

Sarcoma of the Mastoid

Neoplasms Involving the Middle Ear

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