Primary carcinoid tumour of the testis: A case-report

Abstract

Testicular carcinoid tumours (TCT) account for less than 1% of all testicular neoplasms. A 17-year-old male underwent radical orchiectomy for a painful indurated and increased in size right testicle; a mixed echogenic mass, with a central homogeneous area surrounded by a hypoechoic edge with calcifications was found at ultreasound with increased vascularity at color Doppler examination. Biochemical markers were within normal limits. These symptoms are not specific and the majority of TCT are only diagnosed on histopathology. Patients should undergo long-term biochemical and radiological follow-up given potential for delayed metastases, in one case 17 years after primary treatment.

Complete remission of Cdx-2 positive primary testicular carcinoid tumor: 10-years follow-up and literature review

“…Historically, the nomenclature of “carcinoid” was describing the tumor entity of neuroendocrine cells with low malignancy in the gastrointestinal tract (GI) [ 7 ]. However the histopathogenesis of the primary testicular carcinoid remains under debate suggesting respective hypothesis: originating from the same precursor cell as the Leydig cells do or resulting from chromosomal irregularity [ 8 , 9 ].…”

Primary Carcinoid Tumor of the Testis: A Case Report and Review of the Literature

“…The term “carcinoid” was used to indicate a group of tumors in the small intestine arising from neuroendocrine (NE) cells having low malignant potential [12]. There is still debate concerning the carcinogenesis of primary testicular carcinoid tumors since the presence of NE cells in the testis has not been yet described with hypotheses postulating the origin to be the same precursor cell as Leydig cells, while others attributing it to a chromosomal abnormality [7, 13].…”