Primary calcification in post-transplantation lymphoproliferative disorder involving the hepatic graft: an exceptional finding

Abstract

Calcification within active post-transplantation lymphoproliferative disorders has, to our knowledge, never been described. We report the case of a 14-month-old boy who presented 4 months after orthotopic liver transplantation with a primary calcification in a lymphoproliferative nodule involving the hepatic graft. This calcification was detected by routine ultrasonography, visible on plain radiographs, and the post-transplantation lymphoproliferative disorder was histologically proved.

Hepatic and Perihepatic Involvement in Pneumokonioses and Other Mineral-Induced Diseases

“…An important mechanism of liver calcification posttransplantation is mediated by ischemia-reperfusion injury (Kalantari et al 2007). Masses of posttransplantation lymphoproliferative disorder in a liver graft may primarily calcify (Lecouvet et al 1996).…”

Posttransplant Lymphoproliferative Disorders (PTLDs)

“…Burkitt lymphoma-like PTLD of the monomorphous type was observed in the grafted liver following OLT (Ulu et al 2007). In child with liver transplantation, liver nodules of PTLD underwent primary calcification (Lecouvet et al 1996). Plasmacytoma-like PTLD has also been observed to develop in the liver graft following liver transplantation (Vishnu et al 2011).…”