Primary breast angiosarcoma in a postmenopausal female

Vimugdha, Premi; Shubhangi, Arya; Syed, Anjum; Kumari, Gangotri; Varghese, Rosemol; Sharda, Prateek; Ravi, Bina

doi:10.1111/tbj.14009

Cited by 2 publications

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“…[ 10 ] A Schwannoma, lymphoma, angiosarcoma or metastasis should also be kept in mind while making a differential. [ 10 11 12 13 ] In our case, FNAC indicated the borderline phyllodes tumour, however, the demonstration of apocrine morphology with invasive ductal carcinoma on core-needle biopsy confirmed the diagnosis of AC. [ 2 ]…”

Section: Discussionmentioning

confidence: 70%

“…It is said that AR controls the GCDFP-15 production, and hence, is effectively controlled by antiandrogens. [ 13 ] GCDFP-15 positive AC are less aggressive, rarely spread to lymph nodes and have a good prognosis. In the advanced cases of AC, however, the GCDFP-15 level is reported to be decreased, hence, GCDFP-15/AR positivity is not a consistent feature of AC.…”

Section: Discussionmentioning

confidence: 99%

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An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma

Brahmachari

Singh

Arya

2021

Journal of Family Medicine and Primary Care

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A breast mass in women often presents a diagnostic challenge due to the diversity in the diagnosis. We herein report a rare variant of breast carcinoma, an invasive apocrine carcinoma (AC), in an elderly woman where the breast mass clinically mimicked phyllodes tumour. Immunohistochemistry (IHC) showed the tumour as triple-negative and also negative for androgen receptor (AR). Gross cystic disease fluid protein (GCDFP-15) was strongly and diffusely positive. It is an exceptional finding. It implies its significance as a diagnostic marker of AC of the breast. The accurate diagnostic criteria of AC are still lacking. Patients with breast lumps offer unique challenges and enormous responsibility to primary and family care physicians.

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma

Brahmachari

Singh

Arya

2021

Journal of Family Medicine and Primary Care

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“…Color Doppler may show hypervascularity. [8][9][10][11] MRI of angiosarcoma shows a mass with a hypointense signal on T1WIs and a hyperintense signal on T2WIs. The latter suggests the presence of a vascular channel containing slow-flowing blood.…”

Section: Discussionmentioning

confidence: 99%

Primary Angiosarcoma of the Breast: A Rare Case Report in Postmenopausal Women

Issar¹,

Ravindranath²,

Dewangan³

et al. 2022

Indian J Radiol Imaging

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Primary angiosarcoma (PAS) of the breast is a rare malignant tumor arising from endothelial cells lining the blood vessel and accounts for 0.04% of all breast tumors. It occurs predominantly in young patients usually presenting as nonspecific imaging features and is often overlooked and misdiagnosed at radiology and pathology. Angiosarcoma prognosis is generally poor; however, surgery followed by adjuvant chemotherapy and radiotherapy improves the prognosis. We report a rare case of PAS in a 65-year-old postmenopausal woman. She was diagnosed with PAS based on typical clinical, mammography, ultrasound, and magnetic resonance imaging (MRI) features followed by core biopsy of the lesion. Our case had the unique features of enlarged vessels within and surrounding the lesion in mammography, as well as in MRI, which could be very helpful for future diagnosis of this rare PAS in postmenopausal women.

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Primary breast angiosarcoma in a postmenopausal female

Cited by 2 publications

References 0 publications

An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma

An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma

Primary Angiosarcoma of the Breast: A Rare Case Report in Postmenopausal Women

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