Primary bone non-hodgkin lymphoma of the cervical spine. case report and review.

Undabeitia, José; Noboa, Roberto; Boix, Marc; García, Tomás Sánchez; Panadés, Maria Jose; Nogues, Pere

doi:10.5137/1019-5149.jtn.8520-13.1

Cited by 7 publications

(14 citation statements)

References 15 publications

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“…Pain is the most common symptom (80-95%). Pathological fractures (15-20%), hypoesthesia, paraplegia, bladder and anal sphincter dysfunction could be determined [7].…”

Section: Discussionmentioning

confidence: 99%

Primary bone diffuse B cell lymphoma of the thoracic spine: a rare entity

Akçay

Benek

Yılmaz

et al. 2023

The European Research Journal

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Primary bone lymphoma is a rare entity, accounting for approximately 3-7% of malignant bone tumors, 5% of extra-nodal lymphomas and <1% of all non-Hodgkin lymphomas. Primary spine localized lymphoma is 1.7% of all primary bone lymphomas. A 73 year-old female presented with a two month history of severe backache. T1W and T2W MRI showed a hypointense soft tissue component extending from the left posterior elements to Th7 corpus. The patient underwent Th6-7-8 total laminectomy. Th7-8 extradural mass was totally resected. Excisional biopsy was performed through Th7 left pedicle and vertebroplasty was applied. Significant reduction in pain was seen postoperatively. The patient was diagnosed with diffuse large B cell lymphoma. R-CHOP chemotherapy and local radiotherapy were applied. Any other lesions were not detected after the examinations following 6 months period and it was accepted as primary bone lymphoma.

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“…Pain is the most common symptom (80-95%). Pathological fractures (15-20%), hypoesthesia, paraplegia, bladder and anal sphincter dysfunction could be determined [7].…”

Section: Discussionmentioning

confidence: 99%

Primary bone diffuse B cell lymphoma of the thoracic spine: a rare entity

Akçay

Benek

Yılmaz

et al. 2023

The European Research Journal

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“…However, currently, there is a prevalent agreement that it can be considered PBL when primary involvement site of bone with no evidence of extrabone lesions or any other extrabone lesions 6 months after bone lesion is diagnosed by both pathological morphology and immunohistochemistry. [4] Non-Hodgkin lymphoma accounts for up to 94% of the PBL [6] ; almost all cases are diffused large B-cell lymphoma among them. [3] The mechanism of non-Hodgkin lymphoma is not definite in clinic.…”

Section: Discussionmentioning

confidence: 99%

“…[3] It is mostly located in femur or pelvis (50%), long bones of upper limbs (20%), and it can also occur in other locations such as ribs, mandible, or scapula (30%). [4] The most common symptoms of PBL are pain and swelling of affected bone. PBL is extremely uncommon in children, with few cases reported in literature.…”

Section: Introductionmentioning

confidence: 99%

Primary bone lymphoma of radius and tibia

Huan

Qi²,

Zhang³

et al. 2017

Medicine

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Rationale:Primary bone lymphoma (PBL) is a rare malignant entity. There is a better survival of PBL than any other malignant bone tumors and extranodal lymphomas.Patient concerns:We report a rare case of PBL involving radius and tibia. The patient was a 14-year-old girl with left forearm pain and swelling after trauma. Six months later after the last chemotherapy and radiotherapy, pain and swelling of left knee was presented.Diagnoses:Radiological imaging revealed a lytic destruction, periosteal reaction, and pathological fracture of radius and tibia with soft tissue mass. Surgical biopsy was performed, and the result of histopathological diagnosis was diffused large B-cell lymphoma (stage IV, group A).Intervention:Chemotherapy combined with radiotherapy was applied before curation.Lessons:Due to its uncommon presentation, PBL should be taken into consideration if differential diagnosis from other bone tumors is necessary in clinic.

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“…3 These percentages reflect the general low incidence of primary bone lymphomas (5% out of all extranodal NHL and 2% out of all lymphomas). 5,6 Lymphoma of the jaw does not have any specific clinical and radiological features; it often appears as an odontogenic process, thus delaying the diagnosis.…”

Section: Introductionmentioning

confidence: 99%

“… 3 These percentages reflect the general low incidence of primary bone lymphomas (∼5% out of all extranodal NHL and 2% out of all lymphomas). 5 6 …”

Section: Introductionmentioning

confidence: 99%

Odontogenic-Like Pain in Partial Edentulism: An Unusual Presentation of Diffuse Large B-Cell Lymphoma of the Mandible

Catania

Belloni²,

Preda

et al. 2021

Indian J Radiol Imaging

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Primary bone lymphoma is a rare entity and it usually occurs in long bones. Primary mandibular involvement is very rare, and it usually shows unspecific features, mimicking odontogenic inflammatory lesions. We present the unusual case of a diffuse large B-cell lymphoma (DLBCL) of the right mandibular body in a 91-year-old woman, who presented with acute pain in the mandibular region initially suspicious for odontogenic abscess. No significant findings were seen on orthopantomography (OPG) and her almost complete edentulism made the diagnosis of abscess unlikely. Computed tomography and magnetic resonance images showed an expansive mass around the right mandibular body with erosion of cortical bone and involving the right mandibular canal and nerve. Final diagnosis of DLBCL was pathologically proven. The presence of odontogenic-like pain in nearly complete edentulism should be suspicious for malignancy, and it needs further diagnostic workup despite the absence of signs on OPG.

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Primary bone non-hodgkin lymphoma of the cervical spine. case report and review.

Cited by 7 publications

References 15 publications

Primary bone diffuse B cell lymphoma of the thoracic spine: a rare entity

Primary bone diffuse B cell lymphoma of the thoracic spine: a rare entity

Primary bone lymphoma of radius and tibia

Odontogenic-Like Pain in Partial Edentulism: An Unusual Presentation of Diffuse Large B-Cell Lymphoma of the Mandible

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