Primary Bone and Metastatic Tumors of the Cervical Spine

Abdu, William A.; Provencher, Michele

doi:10.1097/00007632-199812150-00019

Cited by 83 publications

(36 citation statements)

References 58 publications

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“…Regarding the prevalence of primary tumor sites, breast cancer was followed by prostate cancer (18.2%), lung cancer (13.6%) and colorectal cancer (13.6%). Similar epidemiological data has also been seen in other published studies [21][22]. A probable explanation for the reversal of the prevalence of metastases in the spine between prostate cancer and breast cancer may be due to the indolence of the evolution of the metastatic status of prostate cancer.…”

Section: Discussionsupporting

confidence: 87%

Health Related Quality of Life of Patients with Vertebral Bone Metastasis after Palliative Surgery

Andrade¹

2017

IOSR JNHS

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Section: Discussionsupporting

confidence: 87%

Health Related Quality of Life of Patients with Vertebral Bone Metastasis after Palliative Surgery

Andrade¹

2017

IOSR JNHS

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“…[4][5][6] Cancer from breast, lung, prostate, haemopoietic and renal origins account for the majority of epidural spinal metastases. [7][8][9] The thoracic spine is most commonly affected, followed by the lumbar spine and the cervical spine. 7,10 The mean survival of patients with neoplastic spinal cord compression (SCC) after developing neurological signs is between 3 and 9 months.…”

Section: Introductionmentioning

confidence: 99%

“…[7][8][9] The thoracic spine is most commonly affected, followed by the lumbar spine and the cervical spine. 7,10 The mean survival of patients with neoplastic spinal cord compression (SCC) after developing neurological signs is between 3 and 9 months. [11][12][13][14] Although it has been estimated that over 80% of patients with neoplastic SCC survive no longer than 1 year, a select group of patients may survive for extended periods, sometimes as long as 4-9 years.…”

Section: Introductionmentioning

confidence: 99%

Epidural metastatic spinal cord compression: functional outcome and survival after inpatient rehabilitation

2004

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Study design: Retrospective descriptive study. Objectives: (1) To obtain an overall appraisal of patients with epidural metastatic spinal cord compression (SCC) (1) Clinical records were reviewed and demographic, clinical and functional data were collected according to a protocol. The date of admittance to the SCU, rehabilitation goals, date of discharge and date of death were recorded. (2) The odds ratio (OR) was calculated for all determinants on admittance to the SCU in order to find indicators that predict survival 41 year after discharge from the SCU. An OR X2 was considered to be clinically significant. Results: In total, 131 patients with epidural metastatic SCC were admitted. In all, 117 clinical records were retrieved and 97 clinical records provided complete data. The average age on admittance was 58 years. Among the patients 53% were male. The average Barthel score on admittance was 7.2/20 points. The average length of stay in the SCU was 104 days (3-336). Overall, 66% of the patients were discharged. The average Barthel score on discharge was 12.0 points. The average survival after discharge was 808 (0-3669) days. During their stay on the SCU, seven patients died. At 1 year after discharge, 52% of the patients were still alive. These patients suffered less complications, had been admitted less often to a hospital during rehabilitation, had made better functional progress and had been discharged home more often. A survival 41 year after discharge is related to ASIA D (OR 4.3), MRC 4 and 5 (OR 5.4), tumour in remission (OR 3.8) and independence or partial independence on the Barthel items: dressing (OR 4.3) and making transfers (OR 5.0). Conclusions: Patients with epidural metastatic SCC may benefit from in-patient rehabilitation.

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“…One of the most common sites of skeletal metastases is the vertebrae [2]. Vertebral metastases most commonly occur in the lumbar region [3].…”

Section: Introductionmentioning

confidence: 99%

Osteoblastic and Osteoclastic Metastases in a Single Vertebra-A Rare Presentation

Chand

Chhabra

Mangat

et al. 2015

JCDR

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A 67-year-old male patient presented to the outpatient department with chief complaint of backache since three months which had been gradually progressive and it radiated to the lower limbs. It was aggravated by walking, stooping down and going up the stairs. There was no history of fall or any trauma to the back. Besides, patient had a history of significant weight loss of around 9 kg over the previous three months. He had to strain while micturition. There was no significant past history except that the patient was a known case of hypertension taking antihypertensive regularly.On general examination patient had mild pallor. There was tenderness over the lumbar region but there was no swelling or any deformity. In the left inguinal region a hard lymph node was noticed. Digital rectal examination was suggestive of enlarged prostate which was hard in consistency and asymmetrical. Routine laboratory investigations were normal except that the patient had anemia (Hb-9.4 g/dL). Serum alkaline phosphate levels were Internal Medicine SectionOsteoblastic and Osteoclastic Metastases in a Single Vertebra-A Rare Presentation ABSTRACTMalignancies may produce bony metastases which may be osteoclastic or osteoblastic. Vertebrae are a common site for bony metastases. Prostatic adenocarcinoma is an important source of vertebral metastases that are mainly osteoblastic in nature. As the osteoblastic metastases are developing there is an ongoing osteoclastic activity which is going on at the microscopic level. Presence of gross osteoblastic and osteoclastic lesions, in the same vertebra, have not been reported at the time of presentation. Here a rare case of vertebral metastases is being presented which shows osteoblastic and osteoclastic gross lesions in the same vertebra.

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Primary Bone and Metastatic Tumors of the Cervical Spine

Cited by 83 publications

References 58 publications

Health Related Quality of Life of Patients with Vertebral Bone Metastasis after Palliative Surgery

Health Related Quality of Life of Patients with Vertebral Bone Metastasis after Palliative Surgery

Epidural metastatic spinal cord compression: functional outcome and survival after inpatient rehabilitation

Osteoblastic and Osteoclastic Metastases in a Single Vertebra-A Rare Presentation

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