Primary aspergillosis affecting the tongue of a leukemic patient

Corrêa, Maria Elvira Pizzigatti; Soares, Andresa Borges; Souza, Cármino Antônio de; Cintra, Maria Letícia; Jorge, Jacks; Almeida, Oslei Paes de; Vargas, Pablo Agustı́n

doi:10.1034/j.1601-0825.2003.00883.x

Cited by 11 publications

(4 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Diagnostic confirmation can be made by microbiological and histopathological analysis of the material, using periodic acid Schiff (PAS) or Groccott–Gomori methenamine silver stains [ 12 , 25 ]. Some less invasive techniques can also be helpful in the diagnosis of aspergillosis, such as the investigation of circulating antigens and components of the fungal wall in the patient’s plasma.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Mandibular Aspergillus Osteomyelitis in an Immunocompetent Patient

et al. 2022

View full text Add to dashboard Cite

Aspergillosis is a fungal infection caused by Aspergillus species, which is contracted through spores that colonize the respiratory tract, causing rhinosinusitis and pulmonary infections. Oral aspergillosis is rare and, when present, may cause soft tissue and bone destruction, generally in immunodeficient patients. Mandibular Aspergillus osteomyelitis is even rarer, with few cases reported in the literature. A 57-year-old Caucasian woman was referred for the evaluation of painful recurrent swelling in the anterior mandibular alveolar ridge, with purulent drainage, previously treated with multiple surgical debridement procedures and antibiotics without success. The patient was otherwise systemically healthy. Surgical debridement was performed and histopathological examination showed osteomyelitis associated with Aspergillus species. Therapy with oral itraconazole (400 mg per day) was administered for 3 months, resulting in complete resolution. No recurrence was detected after 15 years of follow-up. The patient was rehabilitated with dental implants. In conclusion, non-bacterial microorganisms, such as Aspergillus, should be considered in cases of mandibular osteomyelitis that do not heal after surgical debridement and antibiotic therapy.

show abstract

Section: Discussionmentioning

confidence: 99%

A Rare Case of Mandibular Aspergillus Osteomyelitis in an Immunocompetent Patient

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Exposure to the fungus Aspergillus fumigata can also produce a disease associated with chronic oral ulcers. This rare condition also mainly affects immunocompromised patients 3,27 …”

Section: Chronic Oral Ulcersmentioning

confidence: 99%

“…This rare condition also mainly affects immunocompromised patients. 3,27 Fungi of the genuses Absidia, Rhizopus, Rhizomucor or Mucor produce zygomycosis, a fungal infection that can give rise to ulcers with a necrotic halo on the palate. Diabetes and immunodeficiency diseases have been related to a higher risk of this infection.…”

Section: Tuberculosismentioning

confidence: 99%

Oral ulcers: clinical aspects. A tool for dermatologists. Part II. Chronic ulcers

Corcuera

Esparza-Gómez

González-Moles

et al. 2009

Clinical and Experimental Dermatology

View full text Add to dashboard Cite

Oral ulcers are generally painful lesions that are related to various conditions developing within the oral cavity. They can be classified as acute or chronic according to their presentation and progression. Acute oral ulcers are be associated with conditions such as trauma, recurrent aphthous stomatitis, Behçet's disease, bacterial and viral infections, allergic reactions or adverse drug reactions. Chronic oral ulcers are associated with conditions such as oral lichen planus, pemphigus vulgaris, mucosal pemphigoid, lupus erythematosus, mycosis and some bacterial and parasitic diseases. The correct differential diagnosis is necessary to establish the appropriate treatment, taking into account all the possible causes of ulcers in the oral cavity. In this second part of this two-part review, chronic oral ulcers are reviewed.

show abstract

“…From here, the fungus may spread to the skin, orbits, nose and palate. However, primary invasive aspergillosis of the oral cavity is uncommon and only a few cases have been reported 1,3–9 …”

Section: Introductionmentioning

confidence: 99%

Invasive oral aspergillosis in a patient with acute myeloid leukaemia

Cho¹,

Kh²,

Colquhoun³

et al. 2010

Australian Dental Journal

View full text Add to dashboard Cite

Aspergillosis (a fungal infection by an organism of the Aspergillus species) of the oral cavity is an uncommon condition which most frequently occurs in immunocompromised patients, such as those with haematological malignancies. In such patients, prolonged neutropenia secondary to chemotherapeutic agents enables the spread of invasive aspergillosis, which is unaffected by anatomical barriers. Early detection and treatment of the condition is essential to avoid more serious complications, such as disseminated infection, which results in increased morbidity and mortality. This case report describes a patient with acute myeloid leukaemia who developed localized invasive Aspergillus flavus of the palate. High-dose antifungal therapy was instituted along with surgical removal of the involved tissues. Aspergillosis of the palate was successfully eradicated with no long-term ill effects from the treatment. Management of invasive aspergillosis includes early aggressive antifungal medication combined with surgical removal of the involved tissues.

show abstract

Primary aspergillosis affecting the tongue of a leukemic patient

Cited by 11 publications

References 17 publications

A Rare Case of Mandibular Aspergillus Osteomyelitis in an Immunocompetent Patient

A Rare Case of Mandibular Aspergillus Osteomyelitis in an Immunocompetent Patient

Oral ulcers: clinical aspects. A tool for dermatologists. Part II. Chronic ulcers

Invasive oral aspergillosis in a patient with acute myeloid leukaemia

Contact Info

Product

Resources

About