Primary Antiphospholipid Syndrome and Evan’s Syndrome: 2 Case Reports

Abstract

The main clinical features of primary antiphospholipid syndrome are recurrent foetal loss, arterial or venous thrombosis and thrombocytopaenia. Evan's syndrome is characterized by simultaneous or sequential association of autoimmune anaemia and thombocytopaenia, rarely reported in primary antiphospholipid syndrome. We describe 2 cases of this association. Treatment with steroids was started in both cases, the follow-up was marked by the normalization of haemoglobin value and platelet count, without relapse.

A Case of Evans Syndrome: A Clinical Condition With Under-Recognized Thrombotic Risk

“…The first patient was a 19-year-old female who presented with acute lower extremity DVT and the other patient was a 36-year-old female with recurrent fetal loss and epistaxis. Both of these patients were treated with intravenous (IV) steroids and had reported resolution of their cytopenias [5]. Each of the unique cases outlined above demonstrates patients meeting the diagnostic criteria for ES, but more importantly, they shared a common feature of a second-hit which increased their risk for thrombosis [6].…”

Trombosis venosa seguida de una hemorragia cerebral en un paciente con síndrome antifosfolipídico

“…Nuestro paciente tenía el antecedente de SE, caracterizado por la asociación de una AHA y trombocitopenia, que no era tratado de manera regular según lo manifestado por el paciente. Existen pocos reportes de la simultaneidad clínica de ambos síndromes [8] .…”