Primary anorectal malignant melanoma with laparoscopic abdominoperineal resection: a case study and review of the relevant literature

The perspectives of molecularly targeted therapies which this issue illustrates

“…The remaining three case reports relate to anti-PD-1 antibodies. Nonaka et al reported a case in which anorectal malignant melanoma was resected but soon had distant metastasis and was treated with nivolumab [2]. Hayakawa et al reported a case in which pembrolizumab was given to a metastatic urothelial carcinoma, and suffered myasthenia gravis [3].…”