Primary Angiosarcoma of the Tongue: A Case Report

Chadha, V. K.; Rawat, Digvijay Singh; Prasad, Beni

doi:10.4236/ijohns.2012.12011

Cited by 6 publications

(10 citation statements)

References 9 publications

(7 reference statements)

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“…A combined modality of treatment, including postoperative radiotherapy, is recommended. The general outcome of primary AS of the oral cavity is good, with a mean survival period of 7.3 to 7.6 years, compared to primary cutaneous and deep soft tissue tumors 6 11 . Our patient underwent surgery and declined oncological treatment.…”

Section: Discussionmentioning

confidence: 97%

“…Immunohistochemical analysis is essential for differentiating AS from similar lesions such as hemangioendothelioma, hemangiopericytoma, epithelioid sarcoma, Kaposi's sarcoma 6 11 , perivascular epithelioid tumor (malignant Pecoma), spindle cell carcinoma, malignant melanoma, intravascular endothelial hyperplasia, epithelioid AS, and lymphangiosarcoma 6 .…”

Section: Discussionmentioning

confidence: 99%

“…Positive staining for factor VII and Ulex europaeus agglutinin has been used to diagnose vascular pathology. CD31, a membrane glycoprotein, is the best vascular marker of endothelial phenotypes, particularly in poorly differentiated AS 11 , where factor VIII and U. europaeus are negative. Positive staining for thrombomodulin and E-selectin also support the diagnosis of AS 11 .…”

Section: Discussionmentioning

confidence: 99%

“…CD31, a membrane glycoprotein, is the best vascular marker of endothelial phenotypes, particularly in poorly differentiated AS 11 , where factor VIII and U. europaeus are negative. Positive staining for thrombomodulin and E-selectin also support the diagnosis of AS 11 . Tumors showing vasoformative channels and intracytoplasmic vacuoles on hematoxylin and eosin sections are likely angiogenic.…”

Section: Discussionmentioning

confidence: 99%

“…Metastatic spread is usually hematogenous, and a common site of involvement is the lungs. Lymphatic spread is reported in less than 20% of ASs involving the head and neck region 11 . In our case, no lymph node involvement or distant metastases were observed at initial presentation or during the follow-up period; however, we did not carry out any lymph node survey.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Primary oral soft tissue angiosarcoma of the cheek: a case report and literature review

Fomete

Samaila

Edaigbini

et al. 2015

J Korean Assoc Oral Maxillofac Surg

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Primary oral soft tissue angiosarcoma of the cheek: a case report and literature review

Fomete

Samaila

Edaigbini

et al. 2015

J Korean Assoc Oral Maxillofac Surg

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A case report of angiosarcoma originating from the tongue

Kusaka,

Katagiri,

Saito

et al. 2023

Clinical Case Reports

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Key Clinical MessageAngiosarcoma is a rare malignant disease with an extremely poor prognosis, showing rapid progression of the local tumor and/or distant metastases. Although multidisciplinary approach including systemic chemotherapy and radiation therapy is ideal for this disease, surgical resection have a role in disease control and should be performed as soon as possible.AbstractAngiosarcomas originating from the tongue are rare and have extremely malignant features, leading to a poor prognosis. Herein, we report the case of a patient with angiosarcoma arising from the tongue who was successfully treated surgically. A 71‐year‐old man was diagnosed with a mass on the right side of his tongue and visited the Department of Oral and Maxillofacial Surgery at our hospital. The patient was referred to our department for further examination and treatment after a biopsy of the right edge of the tongue. An irregularly raised tumor 50 mm in length was noted on the right lingual border. The preoperative diagnosis was a primary angiosarcoma of the tongue (clinical stage, T3N2bM0, Stage IV). As his tumor had been growing rapidly, he emergently underwent partial right‐sided tongue resection and right neck dissection without reconstructive surgery. The histopathological diagnosis was pT3N0. Postoperatively, the patient showed no signs of recurrence or metastasis during the 1‐year follow‐up. As for angiosarcomas, surgical resection is the only curative treatment, and surgery should be performed as soon as possible after the final diagnosis.

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