Primary and Secondary Prevention of Chronic Obstructive Pulmonary Disease: Where to Next?

Young, Robert P.

doi:10.1164/rccm.201405-0883le

Cited by 11 publications

(5 citation statements)

References 8 publications

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“…Lung function is a significant predictor of future morbidity and mortality in the general population 1. Maintaining good lung function across adult life is important to prevent chronic respiratory diseases, which nowadays represent a serious public health problem around the world 2. There is consistent evidence showing that overweight, obesity and weight gain in adulthood are detrimental to lung function, as described by the forced vital capacity (FVC) and/or forced expiratory volume in 1 s (FEV 1 ).…”

Section: Introductionmentioning

confidence: 99%

Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study

Peralta

Marcon

Carsin

et al. 2020

Thorax

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BackgroundPrevious studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate lung function trajectories during adulthood from 20-year weight change profiles using data from the population-based European Community Respiratory Health Survey (ECRHS).MethodsWe included 3673 participants recruited at age 20–44 years with repeated measurements of weight and lung function (forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1)) in three study waves (1991–93, 1999–2003, 2010–14) until they were 39–67 years of age. We classified subjects into weight change profiles according to baseline body mass index (BMI) categories and weight change over 20 years. We estimated trajectories of lung function over time as a function of weight change profiles using population-averaged generalised estimating equations.ResultsIn individuals with normal BMI, overweight and obesity at baseline, moderate (0.25–1 kg/year) and high weight gain (>1 kg/year) during follow-up were associated with accelerated FVC and FEV1 declines. Compared with participants with baseline normal BMI and stable weight (±0.25 kg/year), obese individuals with high weight gain during follow-up had −1011 mL (95% CI −1.259 to −763) lower estimated FVC at 65 years despite similar estimated FVC levels at 25 years. Obese individuals at baseline who lost weight (<−0.25 kg/year) exhibited an attenuation of FVC and FEV1 declines. We found no association between weight change profiles and FEV1/FVC decline.ConclusionModerate and high weight gain over 20 years was associated with accelerated lung function decline, while weight loss was related to its attenuation. Control of weight gain is important for maintaining good lung function in adult life.

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Section: Introductionmentioning

confidence: 99%

Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study

Peralta

Marcon

Carsin

et al. 2020

Thorax

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“…Lung function is a predictor of mortality in the general population, as well as in patients with lung disease, even in those who have never smoked [ 1 ]. Maintaining lung function is an important goal in the prevention of chronic respiratory diseases and a major public health objective; yet, smoking cessation remains the main target to reduce the burden of these diseases [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Dietary antioxidants and 10-year lung function decline in adults from the ECRHS survey

et al. 2017

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The relationship between lung function decline and dietary antioxidants over 10 years in adults from three European countries was investigated.In 2002, adults from three participating countries of the European Community Respiratory Health Survey (ECRHS) answered a questionnaire and underwent spirometry (forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC)), which were repeated 10 years later. Dietary intake was estimated at baseline with food frequency questionnaires (FFQ). Associations between annual lung function decline (mL) and diet (tertiles) were examined with multivariable analyses. Simes’ procedure was applied to control for multiple testing.A total of 680 individuals (baseline mean age 43.8±6.6 years) were included. A per-tertile increase in apple and banana intake was associated with a 3.59 mL·year−1 (95% CI 0.40, 7.68) and 3.69 mL·year−1 (95% CI 0.25, 7.14) slower decline in FEV1 and FVC, respectively. Tomato intake was also associated with a slower decline in FVC (4.5 mL·year−1; 95% CI 1.28, 8.02). Only the association with tomato intake remained statistically significant after the Simes’ procedure was performed. Subgroup analyses showed that apple, banana and tomato intake were all associated with a slower decline in FVC in ex-smokers.Intake of fruits and tomatoes might delay lung function decline in adults, particularly in ex-smokers.

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“…1,2 Although not widely recommended, 3 advocates for screening spirometry in asymptomatic smokers have described this as a "Lung Health Check," an opportunity to identify COPD at a presymptomatic stage and basis for maintaining good lung health through targeted preventive measures. 3,4 Using this approach, these lung cancer screening studies found that between 37% and 67% of their eligible smokers had airflow limitation consistent with COPD. 1,2 In keeping with many community-based studies of high-risk smokers, they also reported that between 50% and 70% of these high-risk smokers with airflow limitation had not yet been diagnosed clinically as having COPD.…”

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confidence: 99%

Incorporating Baseline Lung Function in Lung Cancer Screening

Young

Gamble

Silvestri

2021

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Primary and Secondary Prevention of Chronic Obstructive Pulmonary Disease: Where to Next?

Cited by 11 publications

References 8 publications

Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study

Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study

Dietary antioxidants and 10-year lung function decline in adults from the ECRHS survey

Incorporating Baseline Lung Function in Lung Cancer Screening

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