Primary amenorrhoea in Kashmiri adolescent females – a hospital based study

Abstract

Objectives: The basic aim of this study was to evaluate various causes of primary amenorrhea in Kashmiri adolescent females.Methods and material: the study was conducted in a tertiary care hospital on adolescent females with primary amenorrhoea in the age group of 13-19 years. A detailed history was taken and a thorough examination was done to note the secondary sexual characteristics. All cases were subjected to following investigationshaemoglobin, total leukocyte count, differential leukocyte count, erythrocyte sedimentation rate, coagulation profile and hormonal profile. Radiological investigations and karyotyping were done in selected cases. Statistical analysis: Done by descriptive analysis.Results: Eugonadism was the commonest type of primary amenorrhoea and was seen in 68 cases. Imperforate hymen was seen in 28 cases and complete vaginal atresia in 16. Among hypogonadotropic hypogonadism (23 cases) constitutional delay was seen in 15 cases, 8 cases diagnosed as hypogonadotropic hypogonadism was in fact having thyroid dysfunction. 3 cases with hypergonadotropic hypogonadism were seen and all were diagnosed as Turners syndrome. Conclusions:Though mullerian abnormalities are the most common cause of primary amenorrhoea, thyroid dysfunction should be taken as a possibility in evaluating primary amenorrhoea in an iodine deficient belt like Kashmir.