"Primary" aggressive chondroblastoma of the humerus: a case report

Abstract

Background: Chondroblastomas are rare epiphyseal bone tumors. Very few cases with extracortical aggressive soft tissue invasion or metastasis are reported.

Chondroblastoma of the femoral diaphysis: report of a rare phenomenon and review of literature

“…Not surprisingly, incomplete excision can lead to tumor recurrence in soft tissue due to iatrogenic cortical disruption and/or implantation of tumor cells in the surrounding soft tissue, thereby mimicking primary baggression,Q as described by Harish et al [4]. The same authors recently reviewed the literature on aggressive and atypical CBs and came to the conclusion that only 2 of the previously reported cases were aggressive at the time of initial presentation; the remaining tumors were either rediagnosed as chondrosarcoma or were recurrent CBs.…”

“…Rarely, CBs are termed aggressive, based on the clinical finding of formation of a soft tissue mass, indicating prior cortical breach [4]. bAtypicalQ CBs may also occasionally be encountered.…”

“…bAtypicalQ CBs may also occasionally be encountered. Atypia within a CB is a histologic diagnosis and usually signifies a lesion with staghorn vascularity, myxoid stroma, or a spindle-cell appearance [4].…”

“…There is often a sclerotic rim, a feature which can help refine the differential diagnosis. The tumor may abut or scallop cortical bone but should not breach it, although so-called aggressive CBs may do so [4]. Clinical complaints are often nonspecific; insidious onset of pain is most common [5].…”

Giant chondroblastoma of the femur

“…Наиболее часты местные рецидивы, кото-рые составляют 5-38%, возникают, как правило, внутри кости вследствие неполного удаления первичной опухоли [16] и иногда в мягких тканях [17]. Единичные случаи ХБ гигантского размера описаны у людей с установленным диагнозом, отказывавшихся от лечения и наблюдавшихся в течение 12 лет [7,8]. В 1964 г. Wright описал ХБ у 60-лет-ней женщины, которая впервые отметила опухоль право-го акромиального отростка в 14 лет.…”