Primary Adrenal Lymphoma

Xu, Axiang; Xiao, Xianmin; Ye, Linyang; Hong, Bao-fa; Wang, Xiaoxiong

doi:10.1080/1042819021000047047

Cited by 11 publications

(7 citation statements)

References 11 publications

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“…To our knowledge, there were only five cases of primary adrenal T‐cell lymphoma (PATL) reported in English‐language literatures (Table 2). 7–10 Here we present the sixth case of PATL. Currently, the therapeutic modality for PATL is controversial.…”

Section: Discussionmentioning

confidence: 93%

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Adrenal insufficiency in T‐cell lymphoma

Tsai¹,

Hsieh

Cheng³

et al. 2006

Int J of Urology

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Primary adrenal lymphoma (PAL) is an extremely rare neoplasm of T-cell origin. Here we describe a 42-year-old woman who suffered from intermittent fevers and night sweats of 3 months duration. Laboratory results, imaging, pathology, and immunohistological examination led to a final diagnosis of primary adrenal T-cell lymphoma (PATL) with adrenal insufficiency. The patient received combination chemotherapy and prednisolone but expired 2 months after the treatment. Most reported PAL patients who have received only one therapeutic modality have unsatisfactory survival rates resulting from tumor recurrence and/ or postchemotherapy infections. In contrast, one patient who received an adrenectomy followed by low-dose radiotherapy experienced long-term survival. A combination of therapeutic modalities may improve prognosis for patients with PATL, although the case numbers are too small to draw any conclusions.

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Section: Discussionmentioning

confidence: 93%

“…We reviewed 59 cases of primary adrenal B‐cell lymphoma (PABL) 1,3–6 and six cases of PATL 7–10 from the reported English‐language literature, including our case (Table 1). The reports showed a predilection for elderly men with a mean age at presentation of 54 and 69 years, respectively, as well as a male to female ratio of 3:1.…”

Section: Discussionmentioning

confidence: 99%

Adrenal insufficiency in T‐cell lymphoma

Tsai¹,

Hsieh

Cheng³

et al. 2006

Int J of Urology

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“…Primary endocrine lymphomas are less encountered clinical entities accounting for less than 3% of extranodal lymphomas (8). In particular, PAL is an extremely uncommon condition (9), as opposed to secondary adrenal lymphomas which occur in about 25% of cases of B-cell lymphoma on post-mortem examination (10). They generally present with bilateral adrenal masses with moderate to severe adrenal enlargement (sizes ranging from 30 to 170 mm) (9,11).…”

Section: Discussionmentioning

confidence: 99%

18F-FDG PET/CT Findings in Primary Bilateral Adrenal Lymphoma

et al. 2014

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The adrenal localization of a primary non-Hodgkin lymphoma is rare. We report a case of a 51-year-old man with adrenal insufficiency, cough and elevated eritrosit sedimentation rate. Conventional imaging studies ultrasonography (US) and computed tomography (CT) demonstrated bilateral bulky adrenal masses, and whole-body F-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) showed that the masses and peripancreatic lymphadenopathy were the unique manifestations of this disease. The patient was eventually diagnosed with a diffuse large B-cell non-Hodgkin lymphoma after a CT-guided needle adrenal biopsy. The present case indicated that primary adrenal lymphoma should be included in the differential diagnosis of bilateral adrenal masses.

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“…PET imaging to follow PAL treatment has recently been reviewed [17]. CT findings for PAL have been described as complex cystic due to necrosis and hemorrhage; whereas, secondary lymphoma involvement of the adrenal is more likely to be a homogeneous mass [18]. The adrenal gland is involved in *25% of diffuse lymphoma patients [19,20].…”

Section: Discussionmentioning

confidence: 99%

Primary adrenal natural killer/T‐cell nasal type lymphoma: First case report in adults

et al. 2007

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We report the first case of a primary adrenal natural killer (NK)/T-cell nasal type lymphoma in adults. The patient presented with an enlarging left adrenal mass and the initial concern was for adrenocortical carcinoma. Surgical resection revealed NK/T-cell lymphoma. Rapid recurrence in the contralateral adrenal gland was treated with a single cycle of chemotherapy before he died due to infectious complications and progressive disease. This case demonstrates the aggressive presentation of a novel subset of primary adrenal lymphoma that should be considered in the differential diagnosis of a rapidly enlarging adrenal mass. Am. J. Hematol. 82:299-303, 2007. V V C 2006 Wiley-Liss, Inc.

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Primary Adrenal Lymphoma

Cited by 11 publications

References 11 publications

Adrenal insufficiency in T‐cell lymphoma

Adrenal insufficiency in T‐cell lymphoma

18F-FDG PET/CT Findings in Primary Bilateral Adrenal Lymphoma

Primary adrenal natural killer/T‐cell nasal type lymphoma: First case report in adults

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