Primary Adenosquamous Carcinoma of the Liver on FDG PET/CT

Abstract

Primary adenosquamous carcinoma (ASC) of the liver is a rare subtype of intrahepatic cholangiocarcinoma. Hepatic ASC consists of both adenocarcinoma and squamous cell carcinoma components. Because hepatic ASC is extremely rare, only a few cases describing the imaging findings of hepatic ASC were reported before. Herein, we present FDG PET/CT findings of hepatic ASC in a 78-year-old woman who was admitted to hospital with a 4-week history of right upper quadrant pain.

Unusual Case of Primary Hepatic Squamous Carcinoma on 18F-FDG PET/CT

“…1,[5][6][7] Only a few sporadic cases of primary squamous carcinoma of the liver have been reported, and their PET/CT findings have rarely been described. 8,9…”

“…To date, its pathogenesis remains unclear, and clinical recognition is difficult, relying only on pathology and immunohistochemistry to confirm the diagnosis 1,5–7 . Only a few sporadic cases of primary squamous carcinoma of the liver have been reported, and their PET/CT findings have rarely been described 8,9 …”

Whole-Body 18F-FDG PET/CT Patlak Parametric Imaging of Hepatic Alveolar Echinococcosis

“…Hybrid FDG PET is an established imaging modality for the evaluation of malignant liver tumors but also for inflammatory diseases of the liver. [4][5][6][7][8][9][10] Recent advancements in intrinsic PET scanner sensitivity coupled with increased axial field of view coverage and advanced image reconstruction algorithms have made multibed dynamic acquisitions feasible in clinical practice. [11][12][13][14] Such acquisitions may offer complementary qualitative information and superior quantification over SUV images, through the estimation of pharmacokinetic parameter maps.…”

“…Reconstructed images, together with an aortic input function (IF), were used to generate MR FDG images (DynamicIQ; GE HealthCare), based on traditional Patlak (11 frames, full IF) and relative Patlak (7 frames, partial IF, 29 minutes from 26 minutes postinjection) analysis. Hybrid FDG PET is an established imaging modality for the evaluation of malignant liver tumors but also for inflammatory diseases of the liver 4–10 . Recent advancements in intrinsic PET scanner sensitivity coupled with increased axial field of view coverage and advanced image reconstruction algorithms have made multibed dynamic acquisitions feasible in clinical practice 11–14 .…”