Primary adenocarcinoma of the seminal vesicle

Tanaka, Takuji; Takeuchi, Tashimi; Oguchi, Kenichi; Niwa, Kenji; Mori, Hideki

doi:10.1016/s0046-8177(87)80339-8

Cited by 29 publications

(8 citation statements)

References 11 publications

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“…The combined results of two previous studies found CA-125 immunoreactivity in only 4 of 39 (10%) colon adenocarcinomas (5,24). In the present study, CA-125 staining was absent in all 10 cases of rectal adenocarcinoma tested.…”

Section: Discussionmentioning

confidence: 61%

“…4). Although not repeated in the present study, all four cases of SVCA evaluated were previously reported to be negative for both PSA and PAP (1,(5)(6)(7).…”

Section: Ca-125 Immunoreactivity In Prostatic Adenocarcinoma Bladdermentioning

confidence: 58%

“…Paraffin-embedded formalin-fixed blocks from four previously reported cases of SVCA (1,(5)(6)(7) and one previously reported case of adenocarcinoma arising in a mullerian duct cyst (8) were retrieved. In addition, paraffin-embedded formalin-fixed blocks from three cases of bladder adenocarcinoma from the files of the Cleveland Clinic Foundation were retrieved.…”

Section: Case Selectionmentioning

confidence: 99%

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Primary Seminal Vesicle Carcinoma: An Immunohistochemical Analysis of Four Cases

et al. 2000

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Primary adenocarcinoma of the seminal vesicles is an extremely rare neoplasm. Because prompt diagnosis and treatment are associated with improved long-term survival, accurate recognition of this neoplasm is important, particularly when evaluating limited biopsy material. Immunohistochemistry can be used to rule out neoplasms that commonly invade the seminal vesicles, such as prostatic adenocarcinoma. Previous reports have shown that seminal vesicle adenocarcinoma (SVCA) is negative for prostate-specific antigen (PSA) and prostatespecific acid phosphatase (PAP); however, little else is known of its immunophenotype. Consequently, we evaluated the utility of cancer antigen 125 (CA-125) and cytokeratin (CK) subsets 7 and 20 for distinguishing SVCA from other neoplasms that enter the differential diagnosis.Four cases of SVCA-three cases of bladder adenocarcinoma and a rare case of adenocarcinoma arising in a mullerian duct cyst-were immunostained for CA-125, CK7, and CK20. Three of four cases of SVCA were CA-125 positive and CK7 positive. All four cases were CK20 negative. All bladder adenocarcinomas and the mullerian duct cyst adenocarcinoma were CK7 positive and negative for CA-125 and CK20. In addition, CA-125 immunostaining was performed in neoplasms that commonly invade the seminal vesicles, including prostatic adenocarcinoma (n ‫؍‬ 40), bladder transitional cell carcinoma (n ‫؍‬ 32), and rectal adenocarcinoma (n ‫؍‬ 10), and all were negative for this antigen.In conclusion, the present study has shown that the CK7-positive, CK20-negative, CA-125-positive, PSA/PAP-negative immunophenotype of papillary SVCA is unique and can be used in conjunction with histomorphology to distinguish it from other tumors that enter the differential diagnosis, including

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Section: Discussionmentioning

confidence: 61%

“…4). Although not repeated in the present study, all four cases of SVCA evaluated were previously reported to be negative for both PSA and PAP (1,(5)(6)(7).…”

Section: Ca-125 Immunoreactivity In Prostatic Adenocarcinoma Bladdermentioning

confidence: 58%

Section: Case Selectionmentioning

confidence: 99%

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Primary Seminal Vesicle Carcinoma: An Immunohistochemical Analysis of Four Cases

et al. 2000

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“…Ahora bien, algunos de los casos fueron tratados con vesiculectomía aislada 5,6 y siguieron una buena evolución clínica. En ocasiones fue necesario plantear también cistectomía 7 . La radioterapia parece haber sido indicada con carácter paliativo en casos excesivamente avanzados de muy mal pronóstico 8 .…”

Section: Introductionunclassified

Vesiculectomía con prostatectomía parcial laparoscópica en el tratamiento del adenocarcinoma primario de vesícula seminal con transformación carcinomatosa del conducto eyaculador

et al. 2011

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“…1,2 Of the solid tumors, the most common primary neoplasm is adenocarcinoma. Secondary involvement of the seminal vesicles is common in prostatic or rectal carcinoma [3][4][5] ; however, the differential diagnosis between primary and secondary adenocarcinoma can be diffi cult. Benign solid tumors of the seminal vesicle include papillary adenoma, fi broadenoma, and leiomyoma.…”

Section: Introductionmentioning

confidence: 99%

Leiomyoma of the seminal vesicle

et al. 2009

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We report a case of leiomyoma of the seminal vesicle in a 74-year-old man who presented with left hemilumbago. Computed tomography and magnetic resonance imaging revealed a mass containing coarse calcification and low signal intensity areas on T1- and T2-weighted images. The clinical features of previously reported cases of leiomyoma of the seminal vesicle are presented, including those of the present case. There remains a lack of consensus regarding surgical resection of leiomyoma of the seminal vesicle.

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Primary adenocarcinoma of the seminal vesicle

Cited by 29 publications

References 11 publications

Primary Seminal Vesicle Carcinoma: An Immunohistochemical Analysis of Four Cases

Primary Seminal Vesicle Carcinoma: An Immunohistochemical Analysis of Four Cases

Vesiculectomía con prostatectomía parcial laparoscópica en el tratamiento del adenocarcinoma primario de vesícula seminal con transformación carcinomatosa del conducto eyaculador

Leiomyoma of the seminal vesicle

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