1991
DOI: 10.1016/s0022-5347(17)38530-0
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Priapism in Hypogonadal Men Receiving Gonadotropin Releasing Hormone

Abstract: To our knowledge we report the first 2 cases of priapism occurring in hypogonadal men receiving gonadotropin releasing hormone therapy. Hypogonadal patients receiving hormonal therapy should be informed about the possibility of priapism and the importance of early urological consultation.

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Cited by 10 publications
(4 citation statements)
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“…Additionally, androgens have been implicated as an important etiologic factor. There are reports of priapism among men with hypogonadism receiving gonadotropin-releasing hormone or high-dose testosterone, adolescents with SCA receiving testosterone, and men using androstenedione to enhance athletic performance [23][24][25][26]. Table 1 presents a classification of ischemic priapism by etiology, as agreed upon by the AFUD-TLP [1••].…”
Section: Etiology and Epidemiologymentioning
confidence: 99%
“…Additionally, androgens have been implicated as an important etiologic factor. There are reports of priapism among men with hypogonadism receiving gonadotropin-releasing hormone or high-dose testosterone, adolescents with SCA receiving testosterone, and men using androstenedione to enhance athletic performance [23][24][25][26]. Table 1 presents a classification of ischemic priapism by etiology, as agreed upon by the AFUD-TLP [1••].…”
Section: Etiology and Epidemiologymentioning
confidence: 99%
“…44 Ironically, GNRH has also been associated with priapism. 45 Similarly, an antiandrogen such as Casodex TM or Flutemide TM can be administered. Enhancement of smooth muscle tone can be achieved with sustained-released alpha 1 agonist administration that is usually packaged along with an antihistamine.…”
Section: Therapy For Low¯ow Priapismmentioning
confidence: 99%
“…Recently, very unusual cases of priapism occurring in hypogonadal men receiving pulsatile GnRH therapy for hypogonadotrophic hypogonadism have been described (Whalen et al 1991). The investigators believe that priapism may have developed as a result of sudden exposure to testosterone after prolonged deprivation and/or a diDrug Safety 8 (4) /993 minished threshold response to the androgen hormone.…”
Section: What Is Disease Flare and Its Importance?mentioning
confidence: 99%