PREX proteins level correlation with insulin resistance markers and lipid profile in obese and overweight non-diabetic patients
N. Hamza,
A. A. Kasim,
W. E. Hameed
Abstract:Metabolic dysregulation and obesity are associated with many metabolic alterations, including impairment of insulin sensitivity and dyslipidemia. Recent studies highlight the key role of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchange proteins (PREX proteins) in the pathogenesis of obesity, advocating further elucidation of their potential therapeutic implications. The present study aimed to estimate the serum level of PREX proteins and its potential association with insulin resistance markers a… Show more
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