Previously identified and unidentified polybrominated biphenyl congeners in serum from people living in an electronic waste dismantling area in China

Thyroid Dysfunction of Zebrafish (Danio rerio) after Early-Life Exposure and Discontinued Exposure to Tetrabromobiphenyl (BB-80) and OH-BB-80

“…Polybrominated biphenyls (PBBs) had been historically used extensively as additives in flame retardants for various products, including synthetic fibers, thermoplastics, building materials, foam padding, and electronic appliances until the ban of their commercial production in the United States in 1976. − PBB derivatives are readily formed from numerous abiotic and biotic processes in the biota and environmental matrices. − Because of their extreme stability to sustain heat and degradation, PBBs are highly persistent in the environment, and their residues have still been detected in various abiotic matrices, − as well as in human serum, breast milk, and adipose tissue. ,, The reported screening values or cleanup goals for PBBs in drinking water or groundwater from the Technical Fact Sheet of PBBs released by the U.S. Environmental Protection Agency in 2017 range from 0.0001 to 5 μg/L . Concentrations of PBBs measured in adipose tissues of women in Spain and European countries are over 0.35 ng/g lipid weight, and 3,3′,5,5′-tetrabromobiphenyl (BB-80) contributes ≥90% .…”