Previous thyroid disease and risk of thyroid cancer in Switzerland

Levi, Fabio; Franceschi, Silvia; Vecchia, Carlo La; Negri, Eva; Gulie, Cristina; Duruz, Germaine; Scazziga, B

doi:10.1016/0277-5379(91)90069-p

Cited by 51 publications

(23 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The relationship of thyroid cancer to endemic goiter is widely accepted (69,70). In agreement, it was found a geographical correlation between endemic areas for goiter and thyroid cancer.…”

Section: Iodine Intake and Thyroid Cancermentioning

confidence: 61%

“…In agreement, it was found a geographical correlation between endemic areas for goiter and thyroid cancer. A higher incidence of thyroid cancer was found in England, Wales and Switzerland in areas with endemic goiter (70,71). However, no association was found in the United States between goitrous and non-goitrous areas (72).…”

Section: Iodine Intake and Thyroid Cancermentioning

confidence: 92%

See 1 more Smart Citation

Relevance of iodine intake as a reputed predisposing factor for thyroid cancer

Knobel

Medeiros‐Neto

2007

Arq Bras Endocrinol Metab

View full text Add to dashboard Cite

Iodine is a trace element that is essential for the synthesis of thyroid hormone. Both chronic iodine deficiency and iodine excess have been associated with hypertrophy and hyperplasia of follicular cells, attributed to excessive secretion of TSH. This may be associated to thyroid cancer risk, particularly in women. Experimental studies have documented thyroid cancer induction by elevation of endogenous TSH, although in a small number of animals. Iodine deficiency associated with carcinogenic agents and chemical mutagens will result in a higher incidence of thyroid malignancy. Inadequate low iodine intake will result in increased TSH stimulation, increased thyroid cell responsiveness to TSH, increased thyroid cell EGF-induced proliferation, decreased TGFβ 1 production and increased angiogenesis, all phenomena related to promotion of tumor growth. Epidemiological studies associating iodine intake and thyroid cancer led to controversial and conflicting results. There is no doubt that introduction of universal iodine prophylaxis in population previously in chronic iodine-deficiency leads to a changing pattern of more prevalent papillary thyroid cancer and declining of follicular thyroid cancer. Also anaplastic thyroid cancer is practically not seen after years of iodine supplementation. Iodine excess has also been indicated as a possible nutritional factor in the prevalence of differentiated thyroid cancer in Iceland, Hawaii and, more recently, in China. In conclusion: available evidence from animal experiments, epidemiological studies and iodine prophylaxis has demonstrated a shift towards a rise in papillary carcinoma, but no clear relationship between overall thyroid cancer incidence and iodine intake.

show abstract

“…The relationship of thyroid cancer to endemic goiter is widely accepted (69,70). In agreement, it was found a geographical correlation between endemic areas for goiter and thyroid cancer.…”

Section: Iodine Intake and Thyroid Cancermentioning

confidence: 61%

Section: Iodine Intake and Thyroid Cancermentioning

confidence: 92%

Relevance of iodine intake as a reputed predisposing factor for thyroid cancer

Knobel

Medeiros‐Neto

2007

Arq Bras Endocrinol Metab

View full text Add to dashboard Cite

show abstract

“…19,24,27,29,30,[49][50][51] Possible potential bias in reporting of previous thyroid disease by cases cannot be ruled out, but seems unlikely because the significantly elevated risk was specifically related to goiter or thyroid nodule but not to other thyroid diseases. Our OR estimated for goiter or nodule of 15.0 (95% CI: 3.6-62.7) is consistent with the estimates of 5.9 for a history of goiter and 29.9 for a history of benign nodules/adenomas as reported by Franceschi et al from the international pooled analysis which included our data.…”

Section: Discussionmentioning

confidence: 99%

A Case-control Study in Hiroshima and Nagasaki Examining Non-radiation Risk Factors for Thyroid Cancer

Nagano

Mabuchi

Yoshimoto³

et al. 2007

Journal of Epidemiology

View full text Add to dashboard Cite

“…Concerning the history of benign thyroid disease and risk of thyroid cancer, the majority of studies have demonstrated a strong link between hyperplastic thyroid disease and thyroid cancer (McTiernan et al, 1984;Preston-Martin et al, 1987Ron et al, 1987;Franceschi et al, 1989;Kolonel et al, 1990;Levi et al, 1991;D'Avanzo et al, 1995;Mack et al, 1999); whereas, for hypo-and hyperthyroidism the majority of studies have shown no material association with thyroid cancer. In most case -control studies, the risk estimates have varied between 10 -40 for benign thyroid nodule and 3 -8 for goitre.…”

Section: Epidemiologymentioning

confidence: 99%

Benign thyroid disease and dietary factors in thyroid cancer: a case–control study in Kuwait

2002

View full text Add to dashboard Cite

We conducted a population-based study of 313 case -control pairs in Kuwait to examine the aetiology of thyroid cancer, the second most common neoplasm among women in this and several other countries in the Gulf region. Among the demographic variables, individuals with 12+ years of education had a significantly reduced risk of thyroid cancer (OR=0.6; 95% CI: 0.3 -0.9). The average age at diagnosis (+s.d.) of thyroid cancer was 34.7+11 years in women and 39+13.4 years in men. History of thyroid nodule was reported only by cases (n=34; 10.9%; lower 95% CI: 12.0); and goitre by 21 cases and four controls (OR=5.3; 95% CI: 1.8 -15.3). There was no significant increase in risk with history of hypothyroidism (OR=1.8) or hyperthyroidism (OR=1.7). For any benign thyroid disease, the OR was 6.4 (95% CI: 3.4 -12.0); and the population attributable risk was about 26% (95% CI: 21.1 -30.9). Stepwise regression analysis showed that high consumption of processed fish products (OR=2.2; 95% CI: 1.6 -3.0) fresh fish (OR=0.5; 95% CI: 0.4 -0.7) and chicken (OR=1.7; 95% CI: 1.2 -2.3) were independently associated with thyroid cancer with significant dose-response relationships. Among the thyroid cancer patients who reported high consumption of fish products, a large majority also reported high consumption of fresh fish (98%) and shellfish (68%). No clear association emerged with consumption of cruciferous vegetables. These data support the hypothesis that hyperplastic thyroid disease is strongly related to thyroid cancer; and that habitual high consumption of various seafoods may be relevant to the aetiology of thyroid cancer. The association with chicken consumption requires further study. In most countries, thyroid cancer accounts for approximately 1 -5% of all cancers in females and 52% in males. The age-standardised incidence rates (per 100 000) of thyroid cancer, across most populations, vary from about 2 -10 in females and 1 -3 in males (Parkin et al, 1997). Since the late 1970s, thyroid cancer has consistently been the second most commonly recorded neoplasm (after breast) among Kuwaiti women. During the period 1994 -1998, thyroid cancer accounted for 8.1 and 2.1% of all cancers among Kuwaiti women and men, respectively; and 8.7 and 3.3% of all cancers among non-Kuwaiti (expatriate) women and men, respectively. Similarly high relative frequency and incidence rates of the disease have also been observed in other countries in the Gulf region (Figure 1).Evidence from epidemiological studies suggests that exposure to ionising radiation, especially during childhood and adolescence, is the main risk factor for thyroid cancer (Ron et al, 1995); and history of hyperplastic thyroid disease (i.e., nodule/adenoma and goitre) is an important determinant of the cancer . The study of dietary habits and micro-nutrients in thyroid cancer has been prompted by the essential role of iodine in thyroid function and the potential influence of iodine-rich seafood and goitrogenic vegetables (World Cancer Research Fund, 1997).We conducted a population-b...

show abstract

Previous thyroid disease and risk of thyroid cancer in Switzerland

Cited by 51 publications

References 17 publications

Relevance of iodine intake as a reputed predisposing factor for thyroid cancer

Relevance of iodine intake as a reputed predisposing factor for thyroid cancer

A Case-control Study in Hiroshima and Nagasaki Examining Non-radiation Risk Factors for Thyroid Cancer

Benign thyroid disease and dietary factors in thyroid cancer: a case–control study in Kuwait

Contact Info

Product

Resources

About