1992
DOI: 10.1271/bbb.56.592
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Preventive Effect of Green Tea Polyphenols against Dental Caries in Conventional Rats

Abstract: The effects of green tea polyphenols, inhibitors of various biological activities of cariogenic bacteria in vitro, on caries development were examined using conventional rats. A total of 96 male rats were divided into 8 groups and the rats in the test groups were given tea polyphenols ranging from 0.1% to 0.5% in their cariogenic diet or drinking water for 40 days. Total fissure caries lesions was significantly reduced by the addition of tea polyphenols to the diet or in the drinking water. Diet containing 0.1… Show more

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Cited by 71 publications
(40 citation statements)
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“…No observable toxicity was observed. 133 In yet another study, the dental caries inhibiting effect of the extract from Japanese green tea was studied in vitro and in vivo. The crude tea polyphenolic compounds were found to inhibit the attachment of Streptococcus mutans strain JC-2 (serotype c) to saliva-coated hydroxyapatite discs.…”
Section: P Dental Cariesmentioning
confidence: 99%
“…No observable toxicity was observed. 133 In yet another study, the dental caries inhibiting effect of the extract from Japanese green tea was studied in vitro and in vivo. The crude tea polyphenolic compounds were found to inhibit the attachment of Streptococcus mutans strain JC-2 (serotype c) to saliva-coated hydroxyapatite discs.…”
Section: P Dental Cariesmentioning
confidence: 99%
“…They have recently been discovered to have various physiologically modulating effects such as anti-carcinogenic, [1][2][3][4][5][6][7] anti-metastatic, [8][9][10][11] anti-oxidative, [12][13][14][15] antihypertensive, 16) anti-hypercholesterolemic, [17][18][19] antibacterial, 20) anti-dental caries, [21][22][23] and intestinal flora amelioration activities. 24) Caffeine (1, Fig.…”
mentioning
confidence: 99%
“…Los Streptoccus mutans están asociados con la etiología de las caries dentales (24). Actinomyces spp se encontraron asociadas con las caries radiculares (25), Porphyromonas gingivalis (26,27) (16,17). Varios trabajos demostraron que los polifenoles del té inhiben la actividad de la colagenasa, crecimiento y adherencia celular de Porphyromona gingivalis, conocidos como los factores de virulencia de la enfermedad periodontal (21)(22)(23).…”
Section: Discusionunclassified
“…Estudios recientes sobre los efectos de polifenoles de té verde (catecinas) sobre caries dental mostraron que los polifenoles disminuyen el riesgo de caries in vitro (14,15) e in vivo (16,17).…”
Section: Introductionunclassified