Prevention of Venous Thrombosis and Pulmonary Embolism

Lj, Greenfield; Tw, Wakefield

doi:10.1001/jama.1986.03380060070028

Cited by 450 publications

(3 citation statements)

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“…Considerations for treatment: Pregnant women are five times more likely to experience thromboembolic events than non-pregnant women due to their hypercoagulable status. This danger is related to a hypercoagulable state and venous stasis in the lower extremities brought on by the growing fetus in the womb compressing the inferior vena cava 3,23 . For pregnant women with a history of thromboembolic disease, anticoagulant prophylaxis in the form of low molecular weight heparin is advised to prevent this issue.…”

Section: Hematologic Changesmentioning

confidence: 99%

Protocol for management of pregnant patients requiring emergency minor oral surgical procedures: a prospective study in 52 patients

Jadhav¹,

Shushma²,

Siddiqui³

et al. 2023

JKAOMS

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Objectives: Dental or maxillofacial emergencies are uncommon during pregnancy, but if they occur, they are challenging to treat due to potential risks. The mother should not be denied necessary medical or dental care because of pregnancy. The aim of the study is to observe outcomes of pregnancy in patients requiring emergency minor oral surgical procedures during gestation and to determine the safety of the pregnant woman undergoing the procedure and the fetus. Materials and Methods: The study was conducted on 52 pregnant women requiring emergency oral surgical procedures. A standard treatment protocol for treatment of specific entities was followed. Close monitoring and observation were the primary goal of treatment. All patients were followed postoperatively until complete recovery from the surgical procedures and then until birth of the baby. A control group of 52 healthy pregnant patients who did not require oral surgical procedures was considered for statistical analysis. The measurements to calculate observation were fetal loss (spontaneous abortion), preterm birth, low-birth weight, or incidence of any congenital anomalies in the baby and its association with surgical procedures. Results: No fetal loss occurred in any of the cases. However, four patients experienced preterm birth and seven neonates exhibited low birth weights. No congenital abnormalities were discovered. In one instance, a patient who underwent surgery for a mandibular symphysis fracture under general anesthesia in the 31st week of pregnancy experienced labor pain on the fourth postoperative day, requiring an emergency Caesarean section. Conclusion:The results of our study demonstrate that, compared to the control group, minor emergency surgeries performed during pregnancy have no discernible negative effects on the fetus. These procedures can safely be performed by adhering to our described protocols.

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Section: Hematologic Changesmentioning

confidence: 99%

Protocol for management of pregnant patients requiring emergency minor oral surgical procedures: a prospective study in 52 patients

Jadhav¹,

Shushma²,

Siddiqui³

et al. 2023

JKAOMS

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“…50 The risk of venous thromboembolism is 5x higher in pregnant patients compared to non-pregnant patients. 51,52 Current recommendations for DVT prophylaxis include intraoperative and postoperative pneumatic compression devices, as well as early ambulation. 35 There is limited research regarding the use of chemical prophylaxis in pregnant patients, particularly unfractionated or low-molecular-weight heparin, but heparin can be safely used with monitoring because it does not cross the placenta.…”

Section: Dovepressmentioning

confidence: 99%

Appendicitis During Pregnancy: Best Surgical Practices and Clinical Management

Smolkin,

Kiridly,

Pryor

2023

OAS

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Appendicitis is a common abdominal surgical emergency. However, treatment becomes more complex when the patient is pregnant. It is important to consider the diagnostic differences in pregnant and non-pregnant patients, as well as the changes to surgical and non-surgical management. Commonly, appendicitis in pregnancy is diagnosed with radiographic imaging, preferably ultrasound or MRI. Due to increased risk with delay to surgery, surgical management is recommended, as opposed to non-operative management, and ultimately a laparoscopic appendectomy is the surgery of choice. We aim to provide a comprehensive review of the best practices and clinical management of appendicitis in pregnancy.

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“…The cumulative event rate exceeds 10% by 80 years of age [2] and is associated with substantial mortality and morbidity in the absence of treatment [3]. Clinical symptoms are usually not sufficiently specific for the establishment or exclusion of diagnosis [4]. Objective testing is required to verify clinical suspicion.…”

Section: Introductionmentioning

confidence: 99%

Normal D-Dimer Plasma Level in a Case of Acute Thrombosis Involving Intramuscular Gastrocnemius Vein

Zaki¹,

Elmoheen²,

Elsaeidy³

et al. 2021

Cureus

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Venous thromboembolism (VTE) is a major cause of morbidity and mortality among hospitalized patients. Studies have reported an incidence of deep venous thrombosis to be as high as 50%, especially after craniotomy. Several factors are involved in the alteration of the specificity and sensitivity of D-dimer testing. These include symptom duration, the extent of fibrinolytic and thrombosis activity, anticoagulant therapy, comorbidity associated with medical or surgical illness, cancer, inflammatory diseases, old age, postpartum, and pregnancy period, as well as previous VTE. Several studies have shown the high sensitivity of the Ddimer test (>95%) in pulmonary embolism or acute deep venous thrombosis. The cut-off value is usually within the 500 µg FEU/L range, ruling out acute VTE, especially in patients with low or intermediate clinical probability. Patients who present with a high D-dimer level may necessitate an intense diagnostic approach, the pretest probability notwithstanding. Herein, we present a case of a 52-year-old male patient who presented with a normal D-dimer level in deep venous thrombosis.

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Prevention of Venous Thrombosis and Pulmonary Embolism

Cited by 450 publications

References 0 publications

Protocol for management of pregnant patients requiring emergency minor oral surgical procedures: a prospective study in 52 patients

Protocol for management of pregnant patients requiring emergency minor oral surgical procedures: a prospective study in 52 patients

Appendicitis During Pregnancy: Best Surgical Practices and Clinical Management

Normal D-Dimer Plasma Level in a Case of Acute Thrombosis Involving Intramuscular Gastrocnemius Vein

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