Prevention of peptide fouling on ion-exchange membranes during electrodialysis in overlimiting conditions

Fouling prevention of peptides from a tryptic whey hydrolysate during electromembrane processes by use of monovalent ion permselective membranes

“…Concerning the conventional AMX-SB and CMX-SB membranes, the same observation was noticed and no fouling was detected in the same conditions 11 . It was important to note that the contact duration between the membranes and the WPH in hydrodynamic condition was drastically different from those in static conditions: only one hour compared to overnight.…”

“…The peptide fractions previously obtained for AMX-SB 9 and CMX-SB 10 membranes were re-analysed for peptide identification in the same conditions and with the same equipment as MAP and MCP to be able to compare the UPLC-QTOF results. Figure 1) as in 11 . After ED treatments, MAPs and MCPs were recovered and half of them were soaked separately in 20 mL of 2.0 % (w/w) NaCl in order to remove a potential peptide fouling.…”

“…The freeze-dried NaCl desorption solutions were analyzed by UPLC-QTOF for peptide identification as described in 11 . Moreover, the freeze-dried NaCl desorption solutions of AMX-SB and CMX-SB in static conditions 9, 10 were reanalyzed using this new UPLC-QTOF method in order to be comparable.…”

“…Recent studies showed that conventional food-grade anion-exchange membranes (AMX-SB) and/or cation-exchange membranes (CMX-SB) are exposed to fouling in presence of a WPH either in static 9,10 or in hydrodynamic conditions during an ED process 11 . Fouling was mainly due to a few peptides which could establish electrostatic interactions with the membranes, and that even with no current applied.…”

“…(3) to compare that fouling in terms of quantity and peptide sequences with the conventional membranes from previous studies 9,10,11 carried-out with the same WPH and in the same static and ED conditions.…”