Prevention of non-melanoma skin cancer in organ transplant patients by regular use of a sunscreen: a 24 months, prospective, case-control study

Ulrich, Claas; Jürgensen, Jan Steffen; Degen, Annette; Hackethal, M.; Ulrich, Martina; Patel, Manisha J.; Eberle, Jürgen; Terhorst‐Molawi, Dorothea; Sterry, Wolfram; Stockfleth, Eggert

doi:10.1111/j.1365-2133.2009.09453.x

Cited by 288 publications

(226 citation statements)

References 33 publications

(84 reference statements)

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“…The preventive and therapeutic effect of the use of sunscreen on AKs had already been reported (OR=1.5 for remission and RR = 0.6 for incidence), mainly in places and times of year with high levels of UVR. [60][61][62] Our study presents some limitations as a result of a possible inaccuracy in the clinical diagnosis of AKs and also because the manual counting of lesions produces variable reproducibility. 14,63 Nevertheless, our results prove to be consistent with the data found in the literature and with the pathophysiology of the lesions.…”

Section: Discussionmentioning

confidence: 99%

Oral acetylsalicylic acid and prevalence of actinic keratosis

Schmitt

Miot

2014

Rev. Assoc. Med. Bras.

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Section: Discussionmentioning

confidence: 99%

Oral acetylsalicylic acid and prevalence of actinic keratosis

Schmitt

Miot

2014

Rev. Assoc. Med. Bras.

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“…14,15 In OTRs, regular sunscreen use for 24 months was associated with significant reductions in new SCC and AK occurrences. 16 In addition, habitual use of sunscreens and other photoprotection decreased the rate of subsequent SCCs after a first SCC in OTRs. 17 UV protection is therefore essential for both primary [10][11][12] and secondary prevention of NMSC, and this behaviour should be reinforced in healthy patients as well as in OTRs and others at elevated risk of skin cancer.…”

Section: "I Rarely Bother With Sunscreen"mentioning

confidence: 99%

Non-melanoma Skin Cancer in Canada Chapter 2: Primary Prevention of Non-melanoma Skin Cancer

Barber

Searles

Vender³

et al. 2015

J Cutan Med Surg

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Background: Non-melanoma skin cancer (NMSC), including basal and squamous cell carcinoma (BCC and SCC), represents the most common malignancy. Objective: To provide guidance to Canadian health care practitioners regarding primary prevention of NMSC. Methods: Structured literature searches were conducted, using search terms including prevention, sunscreen, and sun prevention factor. All recommendations concern guidance that physicians should regularly discuss with their patients to help establish photoprotection habits. The GRADE system was used to assign strength to each recommendation. Results: Ultraviolet exposure is the major modifiable risk factor for NMSC. Aspects of photoprotection, including effective sunscreen use and avoidance of both the midday sun and artificial tanning, are discussed. Several widespread misunderstandings that undermine responsible public health measures related to sun safety are addressed. Conclusions: Photoprotection represents both an individual priority and a public health imperative. By providing accurate information during routine patient visits, physicians reinforce the need for ongoing skin cancer prevention. RésuméContexte : De tous les cancers, le carcinome cutané (non-mélanome), y compris le carcinome basocellulaire et le carcinome spinocellulaire, est le plus fréquent. Objectif : Fournir des conseils aux professionnels canadiens de la santé au sujet de la prévention du carcinome cutané. Méthodologie : On a effectué des recherches documentaires structurées à l'aide de divers mots clés, dont « prévention », « écran solaire » et « facteur de protection solaire ». Toutes les recommandations que nous avons repérées portent sur des conseils dont les médecins devraient régulièrement discuter avec leurs patients pour les aider à adopter des habitudes de photoprotection. On a utilisé l'échelle GRADE pour évaluer la pertinence de chacune des recommandations. Résultats : L'exposition aux rayons UV est le plus important facteur de risque modifiable du carcinome cutané. Certains aspects de la photoprotection, entre autres l'utilisation efficace d'un écran solaire, l'évitement du soleil de mi-journée et l'évitement du bronzage artificiel, sont examinés. Plusieurs croyances erronées répandues nuisent aux mesures de santé publique en matière de protection contre le soleil. Conclusions : La photoprotection constitue autant une priorité personnelle qu'un impératif de santé publique. En fournissant des renseignements précis aux patients lors des visites de routine, les médecins insistent sur la nécessité d'une prévention continue du cancer de la peau.

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“…Aktinische Keratosen finden sich vorwiegend an den sonnenexponierten Hautarealen, deren Entstehung wird durch den mutagenen und immunsuppressiven Effekt des UV-Lichtes induziert. Transplantierte Patienten, die regelmässig Sonnenschutzcreme anwendeten (2 mg/cm 2 Hautfläche täglich für zwei Jahre), entwickelten gemäss einer prospektiven Studie signifikant seltener AK [15]. können [17,18].…”

Section: Uv-licht Exposition ((ü2))unclassified