Prevention of Kidney Injury Following Rhabdomyolysis: A Systematic Review

Scharman, Elizabeth J.; Troutman, William G.

doi:10.1345/aph.1r215

Cited by 113 publications

(94 citation statements)

References 67 publications

(133 reference statements)

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“…In the special condition of rhabdomyolysis-related AKI, fluid vascular loading requirements seem to be established [160][161][162], but the nature of the fluid remains in discussion. Theoretical benefits for using sodium bicarbonate are described (inhibition of intrarenal vasoconstriction, inhibition of lipid peroxidation and decreases in myoglobin crystallization with Tamm-Horsfall protein).…”

Section: Rationalementioning

confidence: 99%

Acute kidney injury in the perioperative period and in intensive care units (excluding renal replacement therapies)

Ichai

Vinsonneau

Souweine

et al. 2016

Anaesthesia Critical Care & Pain Medicine

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Acute kidney injury (AKI) is a syndrome that has progressed a great deal over the last 20 years. The decrease in urine output and the increase in classical renal biomarkers, such as blood urea nitrogen and serum creatinine, have largely been used as surrogate markers for decreased glomerular filtration rate (GFR), which defines AKI. However, using such markers of GFR as criteria for diagnosing AKI has several limits including the difficult diagnosis of non-organic AKI, also called "functional renal insufficiency" or "pre-renal insufficiency". This situation is characterized by an oliguria and an increase in creatininemia as a consequence of a reduction in renal blood flow related to systemic haemodynamic abnormalities. In this situation, "renal insufficiency" seems rather inappropriate as kidney function is not impaired. On the contrary, the kidney delivers an appropriate response aiming to recover optimal systemic physiological haemodynamic conditions. Considering the kidney as insufficient is erroneous because this suggests that it does not work correctly, whereas the opposite is occurring, because the kidney is healthy even in a threatening situation. With current definitions of AKI, normalization of volaemia is needed before defining AKI in order to avoid this pitfall.

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Section: Rationalementioning

confidence: 99%

Acute kidney injury in the perioperative period and in intensive care units (excluding renal replacement therapies)

Ichai

Vinsonneau

Souweine

et al. 2016

Anaesthesia Critical Care & Pain Medicine

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“…Intense rehydration as soon as possible and forced alkaline diuresis are also an integral part of the management. In some cases, hemodialysis must be done if needed (3,14,15).…”

Section: Türk Nefroloji Diyaliz Ve Transplantasyon Dergisi Turkish Nementioning

confidence: 99%

Rare Causes of Rhabdomyolysis; Rhabdomyolysis After Epileptic Seizure and Swimming

Taştekin¹,

Sirmatel²,

Şahin³

2018

Turk Neph Dial Transpl

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Rhabdomyolysis is a condition of muscle tissue release including after necrosis of muscle due to a direct or indirect muscle injury. Rhabdomyolysis is mostly asymptomatic but hypovolemic shock, cardiac arrhythmias or acute renal failure may be seen afterwards. Herein, we presented two rare cases of rhabdomyolysis; a patient who developed acute kidney injury associated with rhabdomyolysis following an epileptic seizure and a patient who developed acute kidney injury associated with rhabdomyolysis following swimming. With these rare cases, we wanted to emphasize that epileptic seizures and excessive exercise such as swimming may cause rhabdomyolysis just like the well-known causes. Early treatment of rhabdomyolysis is very important and should be suspected if findings of rhabdomyolysis are seen after these events.

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“…However, the efficacy of this intervention has not been evaluated in randomised trials and routine use is not recommended (17). When performed, urinary alkalinisation should begin once diuresis is underway and should be discontinued if the urine pH does not increase > 6.5 after six hours of infusion or if the arterial pH exceeds 7.5 (5, 18).…”

Section: Treatment and Follow-upmentioning

confidence: 99%

Treningsindusert rabdomyolyse – en pasientserie

Tazmini¹,

Schreiner²,

Bruserud³

et al. 2017

Tidsskriftet

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He contributed to the design, data collection, analysis and interpretation, literature search, drafting and revision of the manuscript and has approved the submitted version. Kiarash Tazmini (born 1976), research fellow. The author has completed the ICMJE form and reports no conflicts of interest. CHRISTOFFER SCHREINER Department of Medicine Diakonhjemmet HospitalHe contributed to the design, data collection, obtaining consent, data interpretation, literature search, drafting and revision of the manuscript and has approved the submitted version. Christoffer Schreiner (born 1985), specialty registrar in internal medicine, and assistant professor. The author has completed the ICMJE form and reports no conflicts of interest. SIDSEL BRUSERUD Department of Medicine Diakonhjemmet HospitalShe contributed to revision of the manuscript and has approved the submitted version. Sidsel Bruserud (born 1980), specialty registrar in internal medicine. The author has completed the ICMJE form and reports no conflicts of interest. TRULS RAASTAD Department of Physical PerformanceNorwegian School of Sport Sciences He contributed to revision of the manuscript and has approved the submitted version. Truls Raastad (born 1968), professor of sports physiology and specialist in sports nutrition, muscle physiology and strength training. The author has completed the ICMJE form and reports no conflicts of interest.

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Prevention of Kidney Injury Following Rhabdomyolysis: A Systematic Review

Cited by 113 publications

References 67 publications

Acute kidney injury in the perioperative period and in intensive care units (excluding renal replacement therapies)

Acute kidney injury in the perioperative period and in intensive care units (excluding renal replacement therapies)

Rare Causes of Rhabdomyolysis; Rhabdomyolysis After Epileptic Seizure and Swimming

Treningsindusert rabdomyolyse – en pasientserie

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