Prevention of Injury to Multiple Casualties Requiring Resuscitation Following Blood Loss

Camp, Frank R.; Dawson, Rhonda

doi:10.1093/milmed/139.11.893

Cited by 10 publications

(5 citation statements)

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“…While reactions have been reported, the incidence and severity of such complications is less than that of not receiving blood or the risk of receiving red cells of the wrong ABO type in emergency situations. During the Vietnam War, the US Army used more than 100,000 units of uncrossmatched group O red cells without a single fatal hemolytic transfusion reaction, and noted that, at the same time, all nine fatal hemolytic transfusion reactions observed in the war occurred with the misidentification of recipients of crossmatched units of red cells or whole blood [30]. …”

Section: Support Of Initial Massive Transfusionmentioning

confidence: 99%

Transfusion medicine in trauma patients

Murthi

Dutton

Edelman

et al. 2008

Expert Review of Hematology

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Injured patients stress the transfusion service with frequent demands for uncrossmatched red cells and plasma, occasional requirements for large amounts of blood products and the need for new and better blood products. Transfusion services stress trauma centers with demands for strict accountability for individual blood component units and adherence to indications in a clinical field where research has been difficult, and guidance opinion-based. New data suggest that the most severely injured patients arrive at the trauma center already coagulopathic and that these patients benefit from prompt, specific, corrective treatment. This research is clarifying trauma system requirements for new blood products and blood-product usage patterns, but the inability to obtain informed consent from severely injured patients remains an obstacle to further research. Keywordsblood bank protocols; clinical blood use; cryoprecipitate transfusion; injury; injury care; plasma transfusion; red cell transfusion; shock resuscitation; transfusion protocols; trauma center protocols Physical injury is the most common cause of death for people in the developed world aged 1-44 years [1]. As a result, injury is the most common cause of loss of years of productive †

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Section: Support Of Initial Massive Transfusionmentioning

confidence: 99%

Transfusion medicine in trauma patients

Murthi

Dutton

Edelman

et al. 2008

Expert Review of Hematology

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“…The time required for blood-type examination and cross-matching might be longer during nights or weekends. We should also consider the following points: (i) withdrawing blood samples from a patient and then transporting them to blood transfusion services will take about 15 min, (ii) transfusing multiple trauma patients with ABO-identical RBCs instead of emergency O-type RBCs is associated with a higher risk of incompatible transfusion (wrong blood in tube) [ 9 ], and (iii) blood testing during nights or weekends by untrained staff can cause errors in blood-type judgment and in clerical work. Therefore, we should transfuse uncross-matched O-type RBCs in extreme emergencies until the blood-type is known, and then transfuse uncross-matched type-specific RBCs.…”

Section: Critical Hemorrhagementioning

confidence: 99%

“…It has been reported that 100,419 units of emergency O-type RBC transfusion during the Vietnam War did not cause lethal complications, while 24 patients who were transfused with cross-matched blood or type-specific blood exhibited lethal hemolytic reactions during the same period owing clerical error [ 9 ]. Dutton et al [ 16 ] have summarized 4 reports and their own results concerning the safety of uncross-matched O-type RBCs in civilian trauma patients.…”

Section: Critical Hemorrhagementioning

confidence: 99%

Risk and crisis management in intraoperative hemorrhage: Human factors in hemorrhagic critical events

Irita

2011

Korean J Anesthesiol

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Hemorrhage is the major cause of cardiac arrest developing in the operating room. Many human factors including surgical procedures, transfusion practices, blood supply, and anesthetic management are involved in the process that leads to hemorrhage developing into a critical situation. It is desirable for hospital transfusion committees to prepare hospital regulations on 'actions to be taken to manage critical hemorrhage', and practice the implementation of these regulations by simulated drills. If intraoperative hemorrhage seems to be critical, a state of emergency should immediately be declared to the operating room staff, the blood transfusion service staff, and blood bank staff in order to organize a systematic approach to the ongoing problem and keep all responsible staff working outside the operating room informed of events developing in the operating room. To rapidly deal with critical hemorrhage, not only cooperation between anesthesiologists and surgeons but also linkage of operating rooms with blood transfusion services and a blood bank are important. When time is short, cross-matching tests are omitted, and ABO-identical red blood cells are used. When supplies of ABO-identical red blood cells are not available, ABO-compatible, non-identical red blood cells are used. Because a systematic, not individual, approach is required to prevent and manage critical hemorrhage, whether a hospital can establish a procedure to deal with it or not depends on the overall capability of critical and crisis management of the hospital.

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“…The risks accrue from potential incompatibility between red cell antigens and serum antibodies. In Vietnam, the US forces transfused Ͼ100,000 units of "universal donor" 25,26 supplied as O-positive whole blood 28,29 with low anti-A and anti-B titers 29 without a single fatality from transfusion reaction (I calculate the 95% upper confidence limit for a zero incidence as 3.0/100,000 units; and the 99% confidence interval as 4.6/100,000 units). 27 However, the vast majority of these were transfused in relatively young males who were unlikely to have been transfused previously.…”

mentioning

confidence: 99%

“…29,37 It was noted in the Vietnam experience that the incidents of hemolytic transfusion reactions when using type-specific blood occurred in clusters when mass casualties were treated. 25,26,29,31 This has led to the supposition that human error induced by the need for speed and multiple simultaneous procedures and transfusions, misaligning recipients, recipients' blood samples, and donor units resulted in major incompatibilities. 29 Different considerations apply to the Rh system.…”

mentioning

confidence: 99%

Emergency Transfusion for Acute Severe Anemia

Weiskopf¹

2010

Anesthesia &Amp; Analgesia

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Prevention of Injury to Multiple Casualties Requiring Resuscitation Following Blood Loss

Cited by 10 publications

References 0 publications

Transfusion medicine in trauma patients

Transfusion medicine in trauma patients

Risk and crisis management in intraoperative hemorrhage: Human factors in hemorrhagic critical events

Emergency Transfusion for Acute Severe Anemia

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