Objectives: The aim of this study is to contribute to the monitoring and treatment in pregnant women with different levels of glucose intolerance by comparing blood glucose profiles and perinatal outcomes. Materials and Methods: A 50-gram Glucose Tolerance Test (GTT) was performed on pregnant women between 24th and 28th weeks of pregnancy who admitted to the outpatient clinic followed by a 100-gram OGTT on those who tested positive with 50 g GTT. The patients were allocated into three groups according to the test results as Normal, Abnormal Glucose Challenge Test (AGCT) and Gestational Diabetes Mellitus (GDM). All groups were evaluated in terms of demographic data, GTT and OGTT results, prenatal and postnatal blood glucose profiles, maternal complications, and perinatal outcomes. Results: The prevalence of AGCT was found to be 17.42% while GDM was 14.57%. When compared as to prepregnancy and during 50 g OGTT values, the body mass index (BMI) was found significantly higher in AGTT group than the normal group (p<0.05). Twenty-four hour and postpartum first 24-hour blood glucose profiles of the AGCT group were found to be higher than the normal group (p<0.05), whereas these values were found to be significantly higher in the GDM group when compared to the AGCT group (p<0.05).
Conclusion:We found that glucose intolerance in the AGCT group was slightly higher when compared to GDM group and appears to be significantly increased when compared to the normal group. Therefore, we suggest that the pregnant women with AGCT should be followed up closely and treated if needed, similar to the patients diagnosed with GDM in order to prevent both fetal and maternal complications.