Prevention of chronic kidney disease: A global challenge

Bello, Aminu K.; Nwankwo, Emeka; Nahas, A. Meguid El

doi:10.1111/j.1523-1755.2005.09802.x

Cited by 163 publications

(133 citation statements)

References 50 publications

(59 reference statements)

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“…Nonetheless, it is thought that in Brazil, as in other countries, the choice of RRT modality is based on clinical condition, as well as on non-medical reasons such as: fi nancial compensation, lack of consistent information to the patient regarding the options, availability of resources and moral, social and cultural aspects. 3 In the present study, 10% of patients began hemodialysis did so with defi nitive vascular access (arteriovenous fi stula); in European countries this rate was 66% and in the USA 15%. 14 In accordance with other studies, 9,16 we found greater survival for patients that underwent renal transplant.…”

Section: Discussionmentioning

confidence: 96%

“…7 The prevalence of 431 pmp found for Brazil is greater than the average of Latin American countries (349 pmp in 2001), 6 but less than in developed countries (700 pmp in Europe and 1403 pmp in the USA) 3 and even those described in countries like Uruguay (809 pmp), Chile (662 pmp) or Argentina (571 pmp). 6 These fi gures suggest that in Brazil a portion of people with ESRD have not been diagnosed or do not have access to health services.…”

Section: Discussionmentioning

confidence: 99%

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Perfil epidemiológico dos pacientes em terapia renal substitutiva no Brasil, 2000-2004

et al. 2010

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OBJECTIVE:To describe the clinical and epidemiological profi le of patients under renal replacement therapies, identifying risk factors for death. METHODS:This is a non-concurrent cohort study of data for 90,356 patients in the National Renal Replacement Therapies Database. A deterministicprobabilistic linkage was performed using the Authorization System for High Complexity/Cost Procedures and the Mortality Information System databases. All patients who started dialysis between 1/1/2000 and 12/31/2004 were included and followed until death or the end of 2004. Age, sex, region of residence, primary renal disease and causes of death were analyzed. A proportional hazards model was used to identify factors associated with risk of death. RESULTS:The prevalence of patients under renal replacement therapies increased an average of 5.5%, while incidence remained stable during the period. Hemodialysis was the predominant initial modality (89%). The patients were majority male with mean age 53 years, residents of the Southeast region and presented unknown causes as the main cause of chronic renal disease, followed by hypertension, diabetes and glomerulonephritis. Of these patients, 42% progressed to death and 7% underwent kidney transplantation. The patients on peritoneal dialysis were older and had higher prevalence of diabetes. The death rate varied from 7% among transplanted patients to 45% among non-transplanted patients. In the fi nal Cox proportional hazards model, the risk of mortality was associated with increasing age, female sex, having diabetes, living in the North and Northeast region, peritoneal dialysis as a fi rst modality and not having renal transplantation. CONCLUSIONS:There was an increased prevalence of patients on renal therapy in Brazil. Increased risk of death was associated with advanced age, diabetes, the female sex, residents of the North and Northeast region and lack of renal transplant.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Perfil epidemiológico dos pacientes em terapia renal substitutiva no Brasil, 2000-2004

et al. 2010

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“…There is significant disparity, however, in ESRD incidence rates between the two continents: Incidence rates are three times higher in the United States compared with Norway and Great Britain (1,2). Data on the prevalence of chronic kidney disease (CKD) in Europe are limited, making it unclear whether the higher ESRD incidence in the United States reflects a higher burden of all stages of CKD (3,4).The relationship between the prevalence of earlier stages of CKD and the incidence of ESRD is complex (5-9): US CKD prevalence has been relatively stable in the past decade, whereas ESRD incidence has increased significantly, and US black patients have a three times higher incidence of ESRD despite similar prevalences of CKD. This can be due to differences in other mechanisms, such as more rapid progression or greater initiation of dialysis.…”

mentioning

confidence: 99%

mentioning

confidence: 99%

International Comparison of the Relationship of Chronic Kidney Disease Prevalence and ESRD Risk

Hallan

Coresh

Astor

et al. 2006

Journal of the American Society of Nephrology

583

340

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ESRD incidence is much lower in. The relative risk for progression from CKD stages 3 or 4 to ESRD in US white patients compared with Norwegian patients was 2.5. This was only modestly modified by adjustment for age, gender, and diabetes. Age and GFR at start of dialysis were similar, hypertension and cardiovascular mortality in the populations were comparable, but US white patients were referred later to a nephrologist and had higher prevalence of obesity and diabetes. In conclusion, CKD prevalence in Norway was similar to that in the United States, suggesting that lower progression to ESRD rather than a smaller pool of individuals at risk accounts for the lower incidence of ESRD in Norway.J Am Soc Nephrol 17: 2275 -2284, 2006 . doi: 10.1681 T here has been a dramatic rise in the number of patients with ESRD in both Europe and North America during the past decades. There is significant disparity, however, in ESRD incidence rates between the two continents: Incidence rates are three times higher in the United States compared with Norway and Great Britain (1,2). Data on the prevalence of chronic kidney disease (CKD) in Europe are limited, making it unclear whether the higher ESRD incidence in the United States reflects a higher burden of all stages of CKD (3,4).The relationship between the prevalence of earlier stages of CKD and the incidence of ESRD is complex (5-9): US CKD prevalence has been relatively stable in the past decade, whereas ESRD incidence has increased significantly, and US black patients have a three times higher incidence of ESRD despite similar prevalences of CKD. This can be due to differences in other mechanisms, such as more rapid progression or greater initiation of dialysis. Early stages of CKD also result in a higher risk for complications, cardiovascular disease, and mortality, which pose a larger absolute risk than ESRD. Furthermore, identifying and treating individuals with early stages of CKD is increasingly proposed for prevention of ESRD and cardiovascular disease (9,10). This requires solid documentation of a high prevalence of preclinical disease. Thus far, European studies on CKD prevalence have been hampered by selection bias or incomplete data for defining CKD stages (11-13).Therefore, there is a need for more information on the prevalence of CKD in European populations as well as a better understanding of the relationship of CKD prevalence to ESRD incidence. The second Health Survey of Nord-Trondelag County (HUNT II) is a large, population-based, cross-sectional study that was conducted in central Norway with a high participation rate (14). We used HUNT II data to assess the prevalence of CKD using calibrated serum creatinine values and repeated measurements of albuminuria. Combining these prevalence estimates with available information on ESRD, health care, and population characteristics, we also examined the extent to which the low incidence of ESRD in Norway compared with the United States reflects a difference in the earlier stages of CKD between the two countries. Material...

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“…Ideally, all adults ought to be routinely screened for evidence of early BEN and associated risk factors. [56] …”

Section: Screening Of Benmentioning

confidence: 99%

Diagnostic Criteria for Balkan Endemic Nephropathy: Proposal by an International Panel

Stefanović¹,

Jelaković²,

Čukuranović³

et al. 2007

Renal Failure

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Balkan endemic nephropathy (BEN) is a familial chronic tubulointerstitial disease with insidious onset and slow progression to terminal renal failure. Diagnostic criteria for BEN have been described more than 40 years ago. Research groups on BEN use one of at least three described lists of criteria. Comparison of studies using such criteria is difficult, and a recent meeting of investigators (Zagreb, October 2006) has suggested that unified criteria have to be elaborated. In this paper, an International Panel of BEN Investigators agreed on criteria appropriate to epidemiologic studies and clinical investigations of BEN. A screening procedure of BEN in endemic settlements is proposed.

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Prevention of chronic kidney disease: A global challenge

Cited by 163 publications

References 50 publications

Perfil epidemiológico dos pacientes em terapia renal substitutiva no Brasil, 2000-2004

Perfil epidemiológico dos pacientes em terapia renal substitutiva no Brasil, 2000-2004

International Comparison of the Relationship of Chronic Kidney Disease Prevalence and ESRD Risk

Diagnostic Criteria for Balkan Endemic Nephropathy: Proposal by an International Panel

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