Prevention in familial breast cancer: counseling and prophylactic mastectomy

Mulvihill, John J.; Safyer, Andrew W.; Bening, Jane K.

doi:10.1016/0091-7435(82)90064-0

Cited by 32 publications

(4 citation statements)

References 22 publications

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“…Among a host of variables tested, including family history of breast cancer and medical and demographic variables, worry was the only variable that predicted RRM surgery. This finding of breast cancer-related worry as a possible variable influencing decision making is consistent with other studies examining RRM (19,24,25,69). No other variable has consistently emerged as a predictor related to RRM decision making.…”

Section: Decision Making: Predictorssupporting

confidence: 90%

Risk-Reduction Mastectomy: Clinical Issues and Research Needs

Stefanek

Hartmann

Nelson

2001

JNCI Journal of the National Cancer Institute

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Risk-reduction mastectomy (RRM), also known as bilateral prophylactic mastectomy, is a controversial clinical option for women who are at increased risk of breast cancer. High-risk women, including women with a strong family history of breast cancer and BRCA1/2 mutation carriers, have several clinical options: risk-reduction surgery (bilateral mastectomy and bilateral oophorectomy), surveillance (mammography, clinical breast examination, and breast self-examination), and chemoprevention (tamoxifen). We review research in a number of areas central to our understanding of RRM, including recent data on 1) the effectiveness of RRM in reducing breast cancer risk, 2) the perception of RRM among women at increased risk and health-care providers, 3) the decision-making process for follow-up care of women at high risk, and 4) satisfaction and psychological status after surgery. We suggest areas of future research to better guide high-risk women and their health-care providers in the decision-making process.

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Section: Decision Making: Predictorssupporting

confidence: 90%

Risk-Reduction Mastectomy: Clinical Issues and Research Needs

Stefanek

Hartmann

Nelson

2001

JNCI Journal of the National Cancer Institute

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“…In addition to the surgical risks of the procedure, significant psychological morbidity may be incurred during the decision-making process and following the procedure. 19 Understanding which factors may cause a woman to regret her decision may help us to counsel patients facing this decision and minimize their regret in the future.…”

mentioning

confidence: 99%

Issues of Regret in Women With Contralateral Prophylactic Mastectomies

et al. 1999

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“…Gene discoveries leading to cancer susceptibility testing have expanded familial cancer risk counseling and education from a few selected centers to becoming widespread in clinical practice (Lynch, et al, 1979; Mulvihill, et al, 1982). The first reports of use of genetic testing information used to inform a family making medical decisions about hereditary breast cancer testing did not occur until 1993 (Biesecker, et al, 1993).…”

Section: Genetic Counseling Across the Lifespanmentioning

confidence: 99%

The genetic self: The Human Genome Project, genetic counseling and family therapy.

Peters¹,

Djurdjinovic²,

Baker³

1999

Families, Systems, & Health

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In the ideal world, genetic counseling, family therapy, and primary healthcare should blend into a seamless network of psychosocial services for families with genetic conditions. The discussions presetered here was inspired by two interdisciplinary workshops titled "The Genetic Self". This paper introduces family therapists and primary care practitioners to the Human Genome Project and current applications in genetic counseling. The practical goal is to foster interdisciplinary teams and referral networks for management of families with or at risk for genetic disorders. Families with genetic conditions may need access to genetic diagnosis, possible genetic testing, tailored medical management, crisis interventions, follow-up at appropriate developmental stages, family therapy, individual psychotherapy, or pastoral counseling for dealing with spiritual issues elicited by

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Prevention in familial breast cancer: counseling and prophylactic mastectomy

Cited by 32 publications

References 22 publications

Risk-Reduction Mastectomy: Clinical Issues and Research Needs

Risk-Reduction Mastectomy: Clinical Issues and Research Needs

Issues of Regret in Women With Contralateral Prophylactic Mastectomies

The genetic self: The Human Genome Project, genetic counseling and family therapy.

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