Prevention Effect in Selenite-Induced Cataract in Vivo and Antioxidative Effects in Vitro of Crataegus pinnatifida Leaves

Wang, Tao; Zhang, Peng; Zhao, Chunfeng; Zhang, Yi; Liu, Hong; Hu, Limin; Gao, Xiumei; Zhang, Deqin

doi:10.1007/s12011-010-8752-8

Cited by 32 publications

(20 citation statements)

References 29 publications

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“…Administration of leaves extract eye drops alternately three times a day in rat pupils with selenite-induced oxidative stress significantly increased serum superoxide dismutase (SOD) and catalase (CAT) activities and tended to reduce malondialdehyde (MDA) level compared with control group. The antioxidant enzymes SOD, CAT, and GSH (glutathione) activities in lens showed a significant increase, thus explains its antioxidant as well as anticataract potential (Wang et al, 2011).…”

Section: Anticataract Potentialmentioning

confidence: 94%

The genus Crataegus: chemical and pharmacological perspectives

Kumar¹,

Arya²,

Bhat³

et al. 2012

Rev. bras. farmacogn.

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Abstract:Traditional drugs have become a subject of world importance, with both medicinal and economical implications. A regular and widespread use of herbs throughout the world has increased serious concerns over their quality, safety and efficacy. Thus, a proper scientific evidence or assessment has become the criteria for acceptance of traditional health claims. Plants of the genus Crataegus, Rosaceae, are widely distributed and have long been used in folk medicine for the treatment of various ailments such as heart (cardiovascular disorders), central nervous system, immune system, eyes, reproductive system, liver, kidney etc. It also exhibits wide range of cytotoxic, gastroprotective, anti-inflammatory, anti-HIV and antimicrobial activities. Phytochemicals like oligomeric procyanidins, flavonoids, triterpenes, polysaccharides, catecholamines have been identified in the genus and many of these have been evaluated for biological activities. This review presents comprehensive information on the chemistry and pharmacology of the genus together with the traditional uses of many of its plants. In addition, this review discusses the clinical trials and regulatory status of various Crataegus plants along with the scope for future research in this aspect.

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Section: Anticataract Potentialmentioning

confidence: 94%

The genus Crataegus: chemical and pharmacological perspectives

Kumar¹,

Arya²,

Bhat³

et al. 2012

Rev. bras. farmacogn.

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“…C. laevigata Fruits Antioxidant [48] C. monogyna Flowers, bearing branches, fruits Antioxidant, negative chronotropic effect [48,49] C. pinnatifida Fruits, leaves Lipid-lowering, anti-inflammatory, against oxidative stress, anticataract potential, immunobiological, hepatoprotective, cytotoxic [21,50] C. meyeri Flower heads Myocardial ischaemia [51] Crataegi folium Leaves Antioxidant [44] C. mexicana…”

Section: Summary Points Lmentioning

confidence: 99%

Mediterranean Hawthorn Fruit (Crataegus) Species and Potential Usage

Çalışkan

2015

The Mediterranean Diet

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“…P. ginseng was shown to abrogate oxidative stress in hepatoma cells and brain cells, as well as in human clinical trials [33], [34], [35]. Additional studies have detailed the antioxidant activities of C. pinnatifida in mouse lymphocytes, rat pups with selenite-induced cataract, and in the livers of high-fat fed mice [36], [37], [38]. Therefore, we hypothesized that GC has protective effects against UVB-induced skin aging.…”

Section: Discussionmentioning

confidence: 98%

Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin

Hwang

Park

Yin

et al. 2017

Journal of Ginseng Research

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BackgroundHuman skin undergoes distinct changes throughout the aging process, based on both intrinsic and extrinsic factors. In a process called photoaging, UVB irradiation leads to upregulation of matrix metalloproteinase-1, which then causes collagen degradation and premature aging. Mixtures of medicinal plants have traditionally been used as drugs in oriental medicine. Based on the previously reported antioxidant properties of Panax ginseng Meyer and Crataegus pinnatifida, we hypothesized that the mixture of P. ginseng Meyer and C. pinnatifida (GC) would have protective effects against skin aging.MethodsAnti-aging activity was examined both in human dermal fibroblasts under UVB irradiation by using Western blot analysis and in healthy human skin by examining noninvasive measurements.ResultsIn vitro studies showed that GC improved procollagen type I expression and diminished matrix metalloproteinase-1 secretion. Based on noninvasive measurements, skin roughness values, including total roughness (R1), maximum roughness (R2), smoothness depth and average roughness (R3), and global photodamage scores were improved by GC application. Moreover, GC ameliorated the high values of smoothness depth (R4), which means that GC reduced loss of skin moisture.ConclusionThese results suggest that GC can prevent aging by inhibiting wrinkle formation and increasing moisture in the human skin.

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Prevention Effect in Selenite-Induced Cataract in Vivo and Antioxidative Effects in Vitro of Crataegus pinnatifida Leaves

Cited by 32 publications

References 29 publications

The genus Crataegus: chemical and pharmacological perspectives

The genus Crataegus: chemical and pharmacological perspectives

Mediterranean Hawthorn Fruit (Crataegus) Species and Potential Usage

Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin

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