Prevention and treatment of recurrent cellulitis

Abstract

Purpose of reviewRecurrent cellulitis is a challenging clinical condition affecting up to 47% of patients after the first episode, especially those with predisposing risk factors. The purpose of this review is to describe the state of the art of literature evidence and to highlight recent developments in its management. Recent findingsRecurrent cellulitis can occur after successful treatment of cellulitis. Conditions that commonly increase the risk of cellulitis include local and systemic modifiable and nonmodifiable factors. A rigorous approach to the management of risk factors and treatment of acute infection is important as the risk of recurrence rises with repeated episodes. Risk factors, if present, need to be targeted in association with antibiotic prophylaxis. Penicillin V is the preferred antibiotic for prevention but other antibiotics and new drugs can be considered in cases of b-lactam allergy, intolerance, or failure.

Skin and soft tissue infections in solid organ transplants

“…An important issue is the prevention of recurrent SSTI, especially in SOT recipients with other comorbidities such as diabetes, venous insufficiency, and obesity. The use of nonpharmacological and pharmacological measures along with the mitigation of predisposing risk factors is crucial [16].…”