Prevention and treatment of different health problems by common peoples diet (Haleem)

Rizwani, Ghazala H.; Abbas, Khizar; Zahid, Hina

doi:10.5897/ajfs2016.1438

Cited by 2 publications

(1 citation statement)

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“…These are distributed in all parts of the plant with variable amounts and variation in the level and chemical composition arise from different genotypes and stages of maturity [6]. Coriander seeds contain significant amounts of several vitamins [7] and minerals [8]. Ethiopian coriander seeds contain essential oils, linalool, -pinene, and geraniol [9].…”

Section: Introductionmentioning

confidence: 99%

Fatty acid and essential oil compositions of seeds of coriander (Coriandrum sativum L.) Cultivated in different regions of Ethiopia

Assefa,

Ele Yaya,

Singh Chandravanshi

et al. 2024

Bull. Chem. Soc. Eth.

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Coriander (Coriandrum sativum L.) seeds are used as spices. In this study, fatty acids extracted from the coriander seeds collected from three places (Sululta, Jimma and Wolaita Sodo) in Ethiopia were determined as their methyl ester using GC-MS. The fatty acid components were assessed using linoleic acid ethyl ester as an external standard. Sululta sample showed five fatty acids, while Wolaita Sodo and Jimma three each with highest amount of petroselinic acid: 68.41%, 72.53%, and 64.4%, respectively, of the total fatty acids. Linoleic acid (omega-6) was found in the range of 18.24-22.37%. The polyunsaturated versus saturated (P/S) index values were found to be 1.69-2.39, which indicated that coriander seeds from the three sites have a good capacity to prevent the development of cardiovascular and some chronic diseases. The number of compounds identified in the essential oils of coriander seeds from Jimma, Sululta, and Wolaita Sodo were 7, 9, and 15 with total percent areas of 99.64, 75.14, and 96.68, respectively. The major component in the essential oils was linalool ranging from 36.72-88.50% of the total amount. In general, the chemical constituents of fatty acids and essential oils of coriander seeds indicates its good nutritional quality and usefulness for human health. KEY WORDS: Coriander seeds, Fatty acids, P/S index, Essential oils, Nutritional quality, Spice Bull. Chem. Soc. Ethiop. 2024, 38(4), 863-876. DOI: https://dx.doi.org/10.4314/bcse.v38i4.4

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Section: Introductionmentioning

confidence: 99%

Fatty acid and essential oil compositions of seeds of coriander (Coriandrum sativum L.) Cultivated in different regions of Ethiopia

Assefa,

Ele Yaya,

Singh Chandravanshi

et al. 2024

Bull. Chem. Soc. Eth.

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The Inhibitory Effect of Three Essential Oils on Candida rugosa Lipase: In Vitro and In Silico Studies

Serseg

Benarous

Yousfi

2020

NPJ

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Background: Essential oils have been used for centuries. EOs are gaining increasing interest because of their acceptance by consumers and their safe status. For the first time, the effect of essential oils on the inhibition of lipases has been investigated in this work. Objective: We aimed in this study to investigate in vitro the inhibitory effects of the three essential oils of most used spices: Peppermint (Mentha piperita L.), cinnamon (Cinnamomum zeylanicum L.) and Cloves (Syzygium aromaticum L. Merr. et Perry) against Candida rugose lipase. In silico studies using molecular docking have been achieved to study the inhibition mechanism of major compounds of EO: menthol, carvacrol, eugenol and cinnamylaldehyde toward CRL. Methods: The inhibitory effect of three essential oils were determined by candida rugosa enzyme and pNP-L as substrate using spectrophotometry. Autodock vina was used for molecular docking with 50 runs. Results: We have found that these essential oils have a strong inhibitory effect with IC50 values 1.09, 1.78 and 1.13 mg/ml compared with Orlistat 0.06 mg/ml. The results show competitive inhibition for the three major compounds Menthol, Carvacrol and Eugenol with uncompetitive inhibition for Cinnamaldehyde. Different repetition ratios of hydrogen bonds and hydrophobic interactions were observed. The saved interactions were with His449, Ser209, Gly123, Gly124 and Phe344 for all molecules. Conclusion: These observations support using and considering essential oils and their major compounds as good sources for design new drugs to treat candidiasis and other diseases related to Lipases.

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Prevention and treatment of different health problems by common peoples diet (Haleem)

Cited by 2 publications

References 76 publications

Fatty acid and essential oil compositions of seeds of coriander (Coriandrum sativum L.) Cultivated in different regions of Ethiopia

Fatty acid and essential oil compositions of seeds of coriander (Coriandrum sativum L.) Cultivated in different regions of Ethiopia

The Inhibitory Effect of Three Essential Oils on Candida rugosa Lipase: In Vitro and In Silico Studies

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