Prevention and treatment of cerebral vasospasm after aneurysmalsubarachnoid hemorrhage

Opančina, Valentina

doi:10.5937/racter8-11415

Cited by 1 publication

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“…However, the amount of data published in this field to date has been relatively limited. Most of the studies explored CVS only in patients who developed neurological symptoms after the procedure [ 12 , 14 , 15 ]. Also, in a great number of other studies, the patient population was heterogeneous, including both those treated surgically and those treated by the endovascular approach [ 16 , 17 ].…”

Section: Introductionmentioning

confidence: 99%

Risk factors for cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage

et al. 2020

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AbstractIntroductionAneurysmal subarachnoid hemorrhage is a type of spontaneous hemorrhagic stroke, which is caused by a ruptured cerebral aneurysm. Cerebral vasospasm (CVS) is the most grievous complication of subarachnoid hemorrhage (SAH). The aim of this study was to examine the risk factors that influence the onset of CVS that develops after endovascular coil embolization of a ruptured aneurysm.Materials and methodsThe study was designed as a cross-sectional study. The patients included in the study were 18 or more years of age, admitted within a period of 24 h of symptom onset, diagnosed and treated at a university medical center in Serbia during a 5-year period.ResultsOur study showed that the maximum recorded international normalized ratio (INR) values in patients who were not receiving anticoagulant therapy and the maximum recorded white blood cells (WBCs) were strongly associated with cerebrovascular spasm, increasing its chances 4.4 and 8.4 times with an increase of each integer of the INR value and 1,000 WBCs, respectively.ConclusionsSAH after the rupture of cerebral aneurysms creates an endocranial inflammatory state whose intensity is probably directly related to the occurrence of vasospasm and its adverse consequences.

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