Preventing Wounds From Healing and Borderline Personality Symptomatology

Sansone, Randy A.; Chang, Joy; Jewell, Bryan

doi:10.4088/pcc.11l01294

Cited by 1 publication

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“…[1][2][3][4][5] BPDs and ASPDs have been found to affect large proportions of offenders (25% of females and 47% of males) and play a significant role in the occurrence of violent crimes. [6][7][8][9][10] These 2 PDs share several comorbidities, including SUDs, [11][12][13][14][15][16][17] impulsivity, 11,13,[18][19][20][21] and aggressiveness. 7,[22][23][24] Moreover, patients with BPD and ASPD are particularly at risk of self-inflicted injury or suicide attempts 6,21 ; these risks increase with impulsivity 6,19,25,26 and SUD.…”

Section: Limitationsmentioning

confidence: 99%

Male Inmate Profiles and Their Biological Correlates

et al. 2014

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Objective:Borderline and antisocial personality disorders (PDs) share common clinical features (impulsivity, aggressiveness, substance use disorders [SUDs], and suicidal behaviours) that are greatly overrepresented in prison populations. These disorders have been associated biologically with testosterone and cortisol levels. However, the associations are ambiguous and the subject of controversy, perhaps because these heterogeneous disorders have been addressed as unitary constructs. A consideration of profiles of people, rather than of exclusive diagnoses, might yield clearer relationships.Methods:In our study, multiple correspondence analysis and cluster analysis were employed to identify subgroups among 545 newly convicted inmates. The groups were then compared in terms of clinical features and biological markers, including levels of cortisol, testosterone, estradiol, progesterone, and sulfoconjugated dehydroepiandrosterone (DHEA-S).Results:Four clusters with differing psychiatric, criminal, and biological profiles emerged. Clinically, one group had intermediate scores for each of the tested clinical features. Another group comprised people with little comorbidity. Two others displayed severe impulsivity, PD, and SUD. Biologically, cortisol levels were lowest in the last 2 groups and highest in the group with less comorbidity. In keeping with previous findings reported in the literature, testosterone was higher in a younger population with severe psychiatric symptoms. However, some apparently comparable behavioural outcomes were found to be related to distinct biological profiles. No differences were observed for estradiol, progesterone, or DHEA-S levels.Conclusions:The results not only confirm the importance of biological markers in the study of personality features but also demonstrate the need to consider the role of comorbidities and steroid coregulation.

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