Preventing Viral Contamination: Effects of Wipe and Spray-based Decontamination of Gloves and Gowns

Robinson, Gwen; Hitchcock, Stephanie; Kpadeh-Rogers, Zegbeh; Karikari, Nicole; Johnson, JK; Blanco, Natalia; Morgan, Daniel J.; Harris, Anthony D.; Leekha, Surbhi

doi:10.1093/cid/ciz622

Cited by 6 publications

(3 citation statements)

References 6 publications

(7 reference statements)

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“…Some studies have investigated the disinfection of textiles and footwear through coarse spray disinfectant application [ 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]. However, few studies have explored the disinfection of textiles and footwear through fine aerosol disinfectant application inside a disinfection chamber.…”

Section: Introductionmentioning

confidence: 99%

Application of an Ultrasonic Nebulizer Closet in the Disinfection of Textiles and Footwear

Henriques

Rito

Proença

et al. 2022

IJERPH

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The emergence of the coronavirus disease 2019 (COVID-19) pandemic highlighted the importance of disinfection processes in health safety. Textiles and footwear have been identified as vectors for spreading infections. Therefore, their disinfection can be crucial to controlling pathogens’ dissemination. The present work aimed to evaluate the effectiveness of a commercial disinfectant aerosolized by an ultrasonic nebulizer closet as an effective method for disinfecting textiles and footwear. The disinfection was evaluated in three steps: suspension tests; nebulization in a 0.08 m3 closet; nebulization in the upscaled 0.58 m3 closet. The disinfection process of textiles and footwear was followed by the use of bacteriophages, bacterial spores, and bacterial cells. The disinfection in the 0.58 m3 closet was efficient for textiles (4 log reduction) when bacteriophage Lambda, Pseudomonas aeruginosa, and Bacillus subtilis were used. The footwear disinfection was achieved (4 log reduction) in the 0.08 m3 closet for Escherichia coli and Staphylococcus aureus. Disinfection in an ultrasonic nebulization closet has advantages such as being quick, not wetting, being efficient on porous surfaces, and is performed at room temperature. Ultrasonic nebulization disinfection in a closet proves to be useful in clothing and footwear stores to prevent pathogen transmission by the items’ widespread handling.

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Section: Introductionmentioning

confidence: 99%

Application of an Ultrasonic Nebulizer Closet in the Disinfection of Textiles and Footwear

Henriques

Rito

Proença

et al. 2022

IJERPH

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“…While a great deal has been published on the disinfection of materials and surfaces for a wide variety of industries, only a few reports exist that are focused on the effectiveness of disinfectants on PPE. [3][4][5] Numerous possibilities exist, including alcohols, heat, and ultraviolet light. [5][6][7][8][9] We focus here on ozone, an easily generated and highly oxidative gas that is widely employed in a variety of applications, including for industrial-scale food disinfection 10 and municipal wastewater treatment.…”

Section: Introductionmentioning

confidence: 99%

Enveloped Virus Inactivation on Personal Protective Equipment by Exposure to Ozone

Blanchard¹,

Lawrence²,

Noble

et al. 2020

Preprint

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Ozone is a highly oxidizing gas easily generated from atmospheric oxygen with inexpensive equipment and is commonly used for the disinfection of municipal water, foods, and surfaces. We report tests of the ability of ozone to inactivate enveloped respiratory viruses (influenza A virus and respiratory syncytial virus), chosen as more easily handled surrogates for SARS-CoV-2, on N95 respirators and other personal protective equipment (PPE) commonly used in hospitals. At 20 ppm, an ozone concentration easily achieved by standard commercial equipment, the viruses were inactivated with high efficiency as long as the relative humidity was above a threshold value of approximately 50%. In the absence of humidity control, disinfection is more variable and requires considerably longer exposure under relatively dry conditions. This report extends the observations of a previous publication (http://doi.org/10.1080/01919510902747969) to hospital-relevant materials and provides additional details about the relationship of humidity to the antiviral activity of ozone. Home CPAP disinfection devices using ozone can provide effective results for individuals. Ozone did not appear to degrade any of the materials tested except for elastic bands if strained during treatment (such as by the pressure exerted by stapled attachment to N95 respirators). The filtration efficiency of N95 respirator material was not compromised.

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“…Disinfecting gloves for reuse would require a complex process that involves physical treatments (e.g., ultraviolet and thermal) or chemical treatment (e.g., alcohol and bleach). Disinfecting gloved hands, − prior to the doffing process, is recommended by the Centers for Disease Control and Prevention (CDC) as a risk-reduction step to avoid self-contamination and surface-contamination during the current COVID-19 pandemic. The disinfection and reuse of gloves are beneficial in that they prolong their service life and, as a result, reduce the need to maintain stockpiles of resupply in order to meet the high operational demand.…”

Section: Introductionmentioning

confidence: 99%

Can Medical-Grade Gloves Provide Protection after Repeated Disinfection?

Esmizadeh

Chang

Jubinville

et al. 2020

ACS Appl. Polym. Mater.

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The advent of the COVID-19 pandemic has generated an increased consumption of personal protective equipment (PPE), including gloves and masks, by healthcare workers and by the general public at a global scale. This has generated substantial shortage of these single-use and disposable PPEs that will end up as a landfill waste. Extending the life cycle of PPEs, such as gloves, by disinfecting treatments could help mitigate these concerns. However, the effect of various disinfection treatments on the functionality of gloves is unknown. In this study, six commonly used viral disinfection treatment methods (i.e., ultraviolet (UV) radiation, dry heat, steam, alcohol, chlorine compounds, and quaternary ammonium compounds) were evaluated for their effect on the performance attributes of two commonly used medical-grade gloves and nitrile and vinyl (latex) gloves. The barrier properties of both gloves against water and ethanol vapor flux were not affected up to 10 cycles of disinfection cycles. However, the increase in the disinfection cycle from 10 to 20 slightly reduced their barrier properties with minor variation in the type of disinfection and glove type. Infrared spectroscopy and microscopy investigations confirmed that both types of gloves could withstand up to 20 cycles of disinfection treatments with no observable change in the chemical structure and surface morphology of the disinfected surfaces, respectively. Lastly, tear property testing of the gloves indicated little to no change from the baseline after 20 cycles of treatment in both the nitrile and vinyl-based gloves. Overall, this study indicated that alcohol, UV, and heat treatment could be acceptable disinfection methods that allow the reuse of gloves up to 20 cycles. Such repeated disinfection of gloves not only reduces the strain on the supply of gloves but also decreases the postconsumer landfilled waste and environmental footprint of gloves.

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Preventing Viral Contamination: Effects of Wipe and Spray-based Decontamination of Gloves and Gowns

Cited by 6 publications

References 6 publications

Application of an Ultrasonic Nebulizer Closet in the Disinfection of Textiles and Footwear

Application of an Ultrasonic Nebulizer Closet in the Disinfection of Textiles and Footwear

Enveloped Virus Inactivation on Personal Protective Equipment by Exposure to Ozone

Can Medical-Grade Gloves Provide Protection after Repeated Disinfection?

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