Preventing HIV infection among injecting drug users in high-risk countries: an assessment of the evidence

Dewhurst, J. Frederic

doi:10.1080/09540120903193757

Cited by 25 publications

(2 citation statements)

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“…In an effort to address the critical role that injection drug use has played in driving HIV transmission in all global regions, clinicians and policy makers have recommended a comprehensive package including harm reduction interventions, addiction treatment, and antiretroviral therapy (ART) targeted towards HIV-positive injection drug-using populations. This public health approach to tackling the health and social harms of injection drug use has been endorsed by the World Health Organization, UNAIDS, and the United Nations Office on Drugs and Crime (UNODC) [4], and draws its design from a large scientific evidence base [5, 6]. …”

Section: Introductionmentioning

confidence: 99%

Injection Drug Use and HIV Antiretroviral Therapy Discontinuation in A Canadian Setting

et al. 2012

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We investigated whether drug-related behaviors predicted antiretroviral therapy (ART) discontinuation among a cohort of injection drug users (IDU) in a Canadian setting. Cox regression analyses were used to investigate the impact of drug use patterns on rates of ART discontinuation among a sample of HIV-positive IDU in Vancouver, Canada between May 1996 and April 2008. In total, 408 HIV-positive IDU initiated ART during the study period, among whom 257 (63.0%) discontinued ART at least once. Rates of ART discontinuation were not significantly elevated among those who reported ongoing injection of heroin, cocaine, or other illicit drugs in comparison to those who reported not injecting drugs. However, public drug use was significantly predictive of ART discontinuation. Our findings may contribute to a reconsideration of the role of active drug use in determining retention in ART programs among IDU.

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Section: Introductionmentioning

confidence: 99%

Injection Drug Use and HIV Antiretroviral Therapy Discontinuation in A Canadian Setting

et al. 2012

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“…Globally, Methadone and Buprenorphine are the most commonly used drugs for opioid substitution therapy. [4] Due to great physical and mental dependency caused by opioid drugs, the vast majority of drug users, relapse after detoxification treatment. The high relapse rate has been affecting the effectiveness of anti-drug work all over the world.…”

Section: Introductionmentioning

confidence: 99%

A Follow up Study Among Patients on Opioid Substitution Therapy (OST) in Terms of Relapse Rate, Factors Affecting Relapse Rate and HCV Incidence

Bala,

Naib,

Singh

et al. 2023

AIMDR

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Background: Many countries are facing a serious problem with opioid dependence. Opioid Substitution Therapy (OST) is prescribed to dependent opioid users to diminish the use and effects of illicitly acquired opioids. The high relapse rate has been affecting the effectiveness of anti-drug work all over the world.Material & Methods:In this study, 200 patients were taken by simple random sampling technique. 100 patient on Buprenorphine substitution therapy and 100 on Methadone maintenance treatment were studied. Patients diagnosed as cases of Opioid dependence as per ICD-10 were selected within the first 3 months and followed up to 1 year at 3, 6 and 9 months. The study was conducted after approval from the institutional ethics and thesis committee. A 14-item questionnaire based on a four-point scale describing the number of times certain events had occurred in the previous week for relapse was used to find factors affecting relapse.Results:The relapse rate among patients in the BPN group at 3, 6 and 9 months relapse was 29.33%, 20.34% and 19.51% while in the Methadone group, it was 24.05%, 15.87% and 12% respectively. The overall HCV Incidence was 75% among patients on Opioid Substitution Therapy. Conclusion:The findings of the study highlight the role of multiple determinants in opioid dependence and relapse. The obtained results showed that HCV infection was an alarming problem among IV opiate drug users in Punjab.

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Dépistage et prévention

Lescanne¹,

Borel²,

Blanchet³

2018

Surdités

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Preventing HIV infection among injecting drug users in high-risk countries: an assessment of the evidence

Cited by 25 publications

References 0 publications

Injection Drug Use and HIV Antiretroviral Therapy Discontinuation in A Canadian Setting

Injection Drug Use and HIV Antiretroviral Therapy Discontinuation in A Canadian Setting

A Follow up Study Among Patients on Opioid Substitution Therapy (OST) in Terms of Relapse Rate, Factors Affecting Relapse Rate and HCV Incidence

Dépistage et prévention

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