Adequate patient education about drug treatment regimen at discharge contributes to the continuity of home care. Integrative review aimed to analyze and synthesize the scientific literature about patient education on medication regimen in the hospital discharge process. We consulted the databases Medical Literature Analysis and Retrieval System on-line (MEDLINE) and Latin-American and Caribbean Center on Health Sciences Information (LILACS), and selected 24 articles published between 2005 and 2010. Inter-related aspects, such as structured discharge planning, medication reconciliation, drug education, adverse drug events and medication adherence, permeate the theme.