Prevent 2nd Stroke: a pilot study of an online secondary prevention program for stroke survivors

Denham, Alexandra M. J.; Halpin, Sean; Twyman, Laura; Guillaumier, Ashleigh; Bonevski, Billie

doi:10.1111/1753-6405.12794

Cited by 13 publications

(13 citation statements)

References 30 publications

(48 reference statements)

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“…Globally, it can be stated that the intake of these food groups in the analysed studies is on an average (e.g. Bailey et al, 2019a, b; Wali et al, 2018) to below average level (Bailey et al, 2019c;Denham et al, 2018). In comparative studies, we can see that the consumption of fruits and vegetables is worse in stroke survivors compared to the healthy group.…”

Section: Discussionmentioning

confidence: 64%

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Eating habits and food composition of stroke survivors as a form of secondary prevention

Mrosková¹,

Reľovská²,

Kuriplachová³

et al. 2021

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Section: Discussionmentioning

confidence: 64%

“…In the Australian intervention study (n = 19), the baseline satisfactory consumption of fruit and vegetables was found in only one respondent (5.3%), and unsatisfactory consumption in 18 respondents (94.7%) -unsatisfactory intake was defined as consuming less than 2 servings of fruit and 5 servings of vegetables per day (Denham et al, 2018).…”

Section: Resultsmentioning

confidence: 99%

Eating habits and food composition of stroke survivors as a form of secondary prevention

Mrosková¹,

Reľovská²,

Kuriplachová³

et al. 2021

Kontakt

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“…However, future implementation of this approach requires greater economic scrutiny over more opportunistic screening at the time of initial hospital management. AuSCR allows direct contact to be made to individuals who had expressed interest in future research, but the 18% response was lower than we had expected (17). This likely reflects our retrospective interrogation of the database for timely identification of a cohort of adequate sample size which consequently delayed the time from the index stroke event, raising the potential for compromised interest and changes to mailing addresses.…”

Section: Discussionmentioning

confidence: 85%

Screening for Fabry Disease in Young Strokes in the Australian Stroke Clinical Registry (AuSCR)

et al. 2020

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Introduction: Fabry disease (FD) is an X-linked lysosomal storage disorder characterized by a deficiency or absence of alpha-galactosidase A (α-GAL A) enzyme, where stroke can be a serious complication. The aim of this study is to determine the feasibility of centralized screening for FD, among young stroke adults registered in the national Australian Stroke Clinical Registry (AuSCR).Methods: The study was conducted in young (age 18 – 55 years) survivors of acute stroke of unknown etiology registered in AuSCR at hospitals in Queensland, Tasmania, New South Wales, and Victoria during 2014 – 2015; and who, at the 3-month outcome assessment, agreed to be re-contacted for future research. Descriptive analyses of case identification from responses and specific enzyme and DNA sequencing analyses were conducted for α-galactosidase A (α-GLA) from dried blood spot (DBS) testing.Results: Of 326 AuSCR-identified patients invited to participate, 58 (18%) provided consent but six were subsequently unable to provide a blood sample and two later withdrew consent to use their data. Among the remaining 50 participants (median age 53 years [48 – 56 years]; 47% female), 67% had experienced an acute ischemic stroke. All males (n = 27) had an initial screen for α-GLA enzyme activity of whom seven with low enzyme levels had normal secondary α-GLA gene analysis. All females (n = 23) had genetic analysis, with one shown to have a pathogenic c.352C>T p.(Arg118Cys) missense mutation of the α-GLA gene for FD.Conclusions: These findings provide logistical data for embedding a process of automated central stroke registry screening for an additional case-finding tool in FD.

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“…This assumes a correlation between the baseline and follow-up HRQoL of 0.6, and a standard deviation of 24 points. Pilot data suggest that approximately 40% of participants recruited at baseline will complete follow-up at 6 months and, therefore, the research team aim to recruit 530 eligible consenting participants at baseline [27].…”

Section: Methodsmentioning

confidence: 99%

An online intervention for improving stroke survivors’ health-related quality of life: study protocol for a randomised controlled trial

Guillaumier

McCrabb

Spratt

et al. 2019

Trials

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Background Recurrent stroke is a major contributor to stroke-related disability and costs. Improving health-risk behaviours and mental health has the potential to significantly improve recovery, enhance health-related quality of life (HRQoL), independent living, and lower the risk of recurrent stroke. The primary aim will be to test the effectiveness of an online intervention to improve HRQoL among stroke survivors at 6 months’ follow-up. Programme effectiveness on four health behaviours, anxiety and depression, cost-effectiveness, and impact on other hospital admissions will also be assessed. Methods/design An open-label randomised controlled trial is planned. A total of 530 adults will be recruited across one national and one regional stroke registry and block randomised to the intervention or minimal care control group. The intervention group will receive access to the online programme Prevent 2nd Stroke (P2S); the minimal care control group will receive an email with Internet addresses of generic health sites designed for the general population. The primary outcome, HRQoL, will be measured using the EuroQol-5D. A full analysis plan will compare between groups from baseline to follow-up. Discussion A low-cost per user option to supplement current care, such as P2S, has the potential to increase HRQoL for stroke survivors, and reduce the risk of second stroke. Trial registration Australian and New Zealand Clinical Trials Registry, ID: ACTRN12617001205325p . Registered on 17 August 2017. Electronic supplementary material The online version of this article (10.1186/s13063-019-3604-0) contains supplementary material, which is available to authorized users.

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Prevent 2nd Stroke: a pilot study of an online secondary prevention program for stroke survivors

Abstract: The results indicated that online programs are an acceptable way to address these health outcomes. Implications to public health: Further research is needed to assess the effectiveness of these interventions using powered trials.

Cited by 13 publications

References 30 publications

Eating habits and food composition of stroke survivors as a form of secondary prevention

Eating habits and food composition of stroke survivors as a form of secondary prevention

Screening for Fabry Disease in Young Strokes in the Australian Stroke Clinical Registry (AuSCR)

An online intervention for improving stroke survivors’ health-related quality of life: study protocol for a randomised controlled trial

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