Prevelance of Bacteria and Candida Oral Colonization Infections Among Dialyzed Patients

Abstract

The prospective study aimed to investigate the incidence of bacteria and Candida infections among dialyzed patients admitted to Saudi Arabian Medical Center (Riyadh City, KSA). A total of 55 of microbial isolates were recovered from 56 different cases by taken oral swab from dialyzed patients. Positive clinical specimens were cultured and identified using standard aerobic microbiological techniques. The conventional Candida identification was used for the identification of the isolated strains. Antimicrobial susceptibility testing of the bacteria and Candida isolates was determined. The results of this study revealed that 33 (60%) of isolates were Gram negative and Gram positive bacteria representing Enterobacter cloacae was the most predominant organisms (21.21%). Out of the 56 studied cases, 22 (40%) were positive for 4 species of the genus Candida isolates. Antimicrobial susceptibility results showed that amikacin, gentamicin, ofloxacin, pfloxacin ciprofloxacin, and imipenem were the more antimicrobial agents effective against the Gram negative isolates. While Gram positive bacterial isolates were sensitive to all antimicrobial agents except gentamicin, clindamycin and metronidazol. Antifungal sensitivity of Candida isolates revealed that C.albicans and C.tropicalis were found to be highly susceptible to azoles whereas isolates of Candida species exhibited decreased susceptibility to amphotericin B.