Prevalencias serológicas para el virus de la diarrea viral bovina y de la rinotraqueítis infecciosa bovina en predios lecheros de la región Metropolitana de Chile

V., María O. Celedón; R., Claudia Vargas; Salinas, Alfonso; G., Adriana Casanova; M., Luis Ibarra; E., Patricio Berríos

doi:10.5354/0716-260x.1996.4774

Cited by 1 publication

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“…Bovine Viral Diarrhea Virus is widely spread in Chilean cattle, with a serological prevalence ranging from 59.7 to 69.2% [ 22 , 23 ], and although an official control of BVDV is not applied in Chile many farmers are using vaccines in order to reduce economic losses. Nevertheless, an effective vaccination strategy against BVDV requires that vaccines reflect the genetic and antigenic types of viruses that infect Chilean cattle.…”

Section: Discussionmentioning

confidence: 99%

“…BVDV infection is widespread among Chilean cattle, with a serological prevalence ranging from 59.7 to 69.2% in unvaccinated animals from different regions of the country [ 22 , 23 ]. To design an effective vaccination strategy against the BVDV virus in Chile, the vaccine strains must match the genetic profile of the viruses that infect Chilean cattle for optimal protection [ 24 , 25 ].…”

Section: Introductionmentioning

confidence: 99%

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Genetic diversity of Bovine Viral Diarrhea Virus from cattle in Chile between 2003 and 2007

et al. 2018

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BackgroundBovine Viral Diarrhea Virus causes significant economic losses in cattle. BVDV has high genomic diversity, with two species, BVDV-1 and BVDV-2, and at least twenty-one subgenotypes for BVDV-1 and four subgenotypes for BVDV-2. Vaccines are important tools to reduce the economic losses caused by this virus. However, vaccine strains must correspond to the antigenic profile of the viruses present in the region where the vaccine is applied. A restricted phylogenetic study with 14 viruses isolated from cattle between 1993 and 2001 showed that the genetic profile of BVDV in Chile consisted of viruses of both species and sub-genotypes 1a, 1b, 1c (currently 1j) and 2a. To determine more accurately the genetic profile of BVDV in Chile, in this study a larger number of viruses obtained from bovines between 2003 and 2007 were typed.ResultsThe study was performed using partial sequences from the 5′ noncoding region (5’UTR) and E2 coding region of the viral genome of thirty-five Chilean viruses isolated from geographic regions that have 84.6% of the Chilean cattle. All tested viruses belonged to species BVDV-1. Eighteen viruses belonged to BVDV-1j subgenotype (51.4%), twelve belonged to BVDV-1b (34.3%) and five belonged to BVDV-1a (14.3%). The Chilean BVDV-1j viruses showed low genetic diversity, both among themselves and with the BVDV-1j present in other regions of the world. This could be explained by a relatively recent introduction of this viral subgenotype in cattle, which agrees with its low geographical distribution worldwide. Otherwise, Chilean BVDV-1b viruses grouped into a single cluster, different even than the viruses present in Argentina and Brazil, countries geographically close to Chile, a process of local evolution that could generate antigenic differences between the Chilean viruses and the viruses used as vaccine strains.ConclusionsThe high presence of viruses of the BVDV-1j subgenotype, which show major antigenic differences with BVDV-1a and BVDV-1b subgenotypes used in the commercial vaccines, suggest that BVDV-1j viruses could be an emergent subgenotype of BVDV in cattle in South America and suggest evaluating an update of the vaccines used in Chile.

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Section: Discussionmentioning

confidence: 99%