Prevalencia de enfermedad renal crónica en España: impacto de la acumulación de factores de riesgo cardiovascular

Gorostidi, Manuel; Sánchez-Martínez, Mercedes; Ruilope, Luís M.; Graciani, Auxiliadora; Cruz, Juan; Santamaría, Rafael; Pino, María Dolores del Pino y; Guallar‐Castillón, Pilar; Álvaro, Fernando de; Rodríguez‐Artalejo, Fernando; Banegas, José R.

doi:10.1016/j.nefro.2018.04.004

Cited by 130 publications

(47 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…If one takes into account that eGFR declines naturally with age, the increased prevalence of CKD in older age groups might be due not only to real CKD but also to a normal biological variation; our findings related to the prevalence by age are thus consistent with multiple previous results [7,[13][14][15]. The possible overestimation of CKD stages in groups with increased age caused by a CKD misclassification is a matter of concern.…”

Section: Discussionsupporting

confidence: 91%

RENA Study: Cross-Sectional Study to Evaluate CKD Prevalence in Portugal

Vinhas¹,

Aires²,

Batista³

et al. 2020

Nephron

View full text Add to dashboard Cite

Introduction: Chronic kidney disease (CKD) is a major global public health problem associated with increased risk of cardiovascular morbidity, premature mortality, and decreased quality of life. In Portugal, the PREVADIAB study showed a prevalence of CKD stages 3-5 of 6.1%. To overcome the limitations of the PREVADIAB study, the RENA study aimed to provide an estimate of the prevalence of CKD at a national level and to characterize CKD patients. Methods: This was a cross-sectional study including users of Primary Health Care Units aged 18 or more. After obtaining written informed consent, sociodemographic and clinical data were recorded through a structured questionnaire, anthropometric measurements were taken, and blood and urine samples were collected. All participants initially meeting the criteria for CKD were contacted at least 3 months after the initial assessment for confirmation of the analytical results. Results: A total of 3,135 individuals were included, 65.4% were female, and the mean age was 56.7 ± 15.9 years. The prevalence of hypertension, dyslipidemia, and diabetes was 38, 32, and 16%, respectively, and 31% were obese. After data adjustment by gender, age group, and geographical region, the global prevalence of CKD was 20.9% (95% CI: 6.5-35.3%), with no differences between genders and a significant increase with the advance of the age groups. Conclusion: Our study showed a CKD prevalence above the worldwide and Europe average. Despite the study limitations, it has become clear that it is urgent to identify CKD patients earlier and to develop awareness and educational programs to prevent CKD and its associated diseases.

show abstract

Section: Discussionsupporting

confidence: 91%

RENA Study: Cross-Sectional Study to Evaluate CKD Prevalence in Portugal

Vinhas¹,

Aires²,

Batista³

et al. 2020

Nephron

View full text Add to dashboard Cite

show abstract

“…Furthermore, between 1990 and 2017, the global all-age mortality rate from CKD increased by 41.5% [ 2 ]. In Spain, CKD is present in 15.1% of individuals and this prevalence is more than three times higher in men than in women (23.1% vs. 7.3%) and increases with age [ 3 ]. Diabetes and hypertension are the main causes of CKD in all high-income and middle-income countries and in many low-income countries [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Potential Drug–Drug Interaction Risk among Chronic Kidney Disease Patients in a Spanish Hospital

et al. 2020

View full text Add to dashboard Cite

Chronic kidney disease (CKD) is a major health problem worldwide and, in Spain, it is present in 15.1% of individuals. CKD is frequently associated with some comorbidities and patients need to be prescribed multiple medications. Polypharmacy increases the risk of adverse drug reactions (ADRs). There are no published studies evaluating the prevalence of potential drug–drug interactions (pDDIs) among CKD patients in any European country. This study was aimed to determine the prevalence, pattern, and factors associated with pDDIs among CKD patients using a drug interactions program. An observational cross-sectional study was carried out at Plasencia Hospital, located in Spain. Data were collected among patients with CKD diagnoses and pDDIs were assessed by the Lexicomp® Drug Interactions platform. Data were obtained from 112 CKD patients. A total number of 957 prescribed medications were acknowledged, and 928 pDDIs were identified in 91% of patients. Age and concomitant drugs were significantly associated with the number of pDDIs (p < 0.05). According to the results, the use of programs for the determination of pDDIs (such as Lexicomp®) is recommended in the clinical practice of CKD patients in order to avoid serious adverse effects, as is paying attention to contraindicated drug combinations.

show abstract

“…12 This obesity rate is lower than the one of Gorostidi's study (22.6%) and in Parikh's one (29.3%). 15,20 Jaroszynski's study showed the existence of a relationship between incidence of CKD and obesity (p<0.001). 21 Obesity contributes to serious morbidities and leads to increased disability and mortality.…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular risk factors in chronic renal failure patient at Soavinandriana Hospital Antananarivo

et al. 2020

View full text Add to dashboard Cite

Background: Cardiovascular disease (CVD) is the primary cause of morbidity and premature mortality in chronic kidney disease (CKD). The aim of this study was to assess the frequency of cardiovascular disease and cardiovascular risk in haemodialysis population for chronic kidney disease.Methods: This was a retrospective and descriptive study for a period of 4 years from January 2016 to December 2019, performed at hemodialysis unit in Soavinandriana Hospital Center Antananarivo, including all patients, following regular hemodialysis for chronic renal failure. Demographic data, cardiovascular disease, cardiovascular risk factors, aetiology of nephropathy, haemoglobin <11 g/dl, phosphocalcic metabolism disorders and uricemia were analyzed.Results: Seventy-six patients were recorded, including 46 males (60.52%) and were women (39.47%). The average age was 59.98 years old. The risk factors of cardiovascular disease were smoking (22.36%), diabetes mellitus (46.05%), high blood pressure (71.05%), dyslipidemia (47.36%) and obesity (11.84%). Fifty-eight patients (76.31%) had a high cardiovascular risk factor. Seventy patients (22.36%) had had a history of cardiovascular diseases. Fifty-nine patients had a haemoglobin concentration under 11 g/dl (77.63%). There were 23 cases of hypocalcemia (30.26%), 22 cases of hyperphosphatemia (28.94%) and 37 cases of hyperuricemia (48.68%).Conclusions: There was a high cardiovascular risk factor in this study population. Early detection of cardiovascular diseases should be done in patients who have a high-risk factor of cardiovascular disease to decrease the mortality rate in chronic kidney diseases population. The appropriate management of modifiable risk factors is important to improve the survival of this study patients.

show abstract

Prevalencia de enfermedad renal crónica en España: impacto de la acumulación de factores de riesgo cardiovascular

Cited by 130 publications

References 20 publications

RENA Study: Cross-Sectional Study to Evaluate CKD Prevalence in Portugal

RENA Study: Cross-Sectional Study to Evaluate CKD Prevalence in Portugal

Prevalence of Potential Drug–Drug Interaction Risk among Chronic Kidney Disease Patients in a Spanish Hospital

Cardiovascular risk factors in chronic renal failure patient at Soavinandriana Hospital Antananarivo

Contact Info

Product

Resources

About