Prevalência de disfunção sexual entre pacientes acompanhadas na coorte Brasília de artrite reumatoide inicial

Costa, Thaís Ferreira; Silva, Carolina Rocha; Muniz, Luciana Feitosa; Mota, Lícia Maria Henrique da

doi:10.1016/j.rbr.2014.10.006

Cited by 16 publications

(12 citation statements)

References 26 publications

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“…This implies that those with better mobility are more likely to successfully integrate into social support networks, maintain good interpersonal relationships, require less help from others in daily activities, and have better sexual function. This finding, however, differed from some other reports [ 10 , 14 ]. This inconsistency may be attributed to the differences in age distribution of study subjects or the use of different statistical analyses.…”

Section: Discussioncontrasting

confidence: 99%

“…The results of our multivariate analysis indicated that older age correlated positively with FSD, in agreement with previous findings [ 8 , 10 , 11 , 14 ]. In general, as females get older, hormone production is lower, and this may cause epithelial atrophy, decline of physical strength, and vaginal dryness, all of which can provoke dyspareunia and decreased libido [ 32 ].…”

Section: Discussionsupporting

confidence: 93%

“…This inconsistency may be attributed to the differences in age distribution of study subjects or the use of different statistical analyses. For example, our subjects (average age: 53.8 years) were older than those in the study of Costa et al (49.7 years) [ 10 ]. It can be argued that different physical and possibly cognitive functions may have different effects on sexual function.…”

Section: Discussionmentioning

confidence: 60%

“…However, some treatments may lead to the onset of negative sequelae, such as fatigue, sadness, and physical changes, and these may influence a patient’s sexual function and desire for sexual intercourse. Previous research estimated that about 46% to 75% of females with RA had female sexual dysfunction (FSD) [ 5 – 9 ], which was approximately twice as high as for the healthy women [ 10 ]. Notably, most women develop RA between the ages of 30 and 50 years, which is within the age range for pregnancy.…”

Section: Introductionmentioning

confidence: 99%

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Factors associated with sexual dysfunction in Taiwanese females with rheumatoid arthritis

Lin

Livneh

et al. 2017

BMC Women's Health

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BackgroundPatients with rheumatoid arthritis (RA) may experience sexual dysfunction because of symptoms or adverse effects from treatments. Data on female sexual dysfunction (FSD) in Asian females with RA issue are limited. This study investigated the prevalence and factors associated with FSD in Taiwanese patients with RA.MethodsThis cross-sectional study used a purposive sampling method to recruit 195 females with RA from a single hospital in southern Taiwan. Demographic and clinical characteristics were obtained by review of medical records and a structured questionnaire. The Chinese version of the Female Sexual Function Index and the Taiwanese Depression Questionnaire were also administered. Multiple logistic regression analysis was used to identify factors associated with FSD.ResultsThe crude and age-standardized prevalence of FSD were 66.8% and 48.2%, respectively. Patients who were older, with a comorbid condition, with more depressive symptoms, and with greater disease activity had a significantly higher risk of FSD.ConclusionOur findings indicate that FSD is more common in Taiwanese individuals with RA who have certain specific demographic and clinical characteristics. These findings may help to identify and facilitate the provision of appropriate interventions to ensure better sexual health in female patients with RA.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 60%

Section: Introductionmentioning

confidence: 99%

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Factors associated with sexual dysfunction in Taiwanese females with rheumatoid arthritis

Lin

Livneh

et al. 2017

BMC Women's Health

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“…With regard to fertility in RA as reported in other reports, 113 a recent study observed unexplained subfertility and anovulation in 48% and 28%, respectively, of 178 women. 114 Moreover, RA itself impairs the sexual function in up to 70% of women, 115 with a direct correlation with the disease activity. 116 Both fertility status and sexual function in males have been poorly investigated, with inconclusive results.…”

Section: Fertility and Sexuality In Ra Patients Treated With Biologicmentioning

confidence: 99%

Personalization of biologic therapy in patients with rheumatoid arthritis: less frequently accounted choice-driving variables

Niccoli

Nannini

Blandizzi

et al. 2018

TCRM

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ObjectiveTo propose appropriate statements that drive the choice of biologic therapies in patients with rheumatoid arthritis (RA), factoring in their impact on the following issues: anti-drug antibody (ADAb) formation, suspicion and management of infections, lupus-like syndrome (LLS), effects on bone mass and sexual sphere, and relationship between RA and periodontal disease (PD).MethodsAn overview of existing evidence was undertaken by an expert panel on behalf of the Italian board for the TAilored BIOlogic therapy (ITABIO). Data were extracted from controlled trials, national registries, national health care databases, post-marketing surveys, and, when required by the paucity of controlled studies, from open-label clinical series. Anti-tumor necrosis factor (anti-TNF) and non-anti-TNF-targeted biologics approved for RA were investigated.ResultsADAb formation is chiefly associated with anti-TNFs, and it is reduced by combination therapy with methotrexate. To date, ADAb titration is not advisable for clinical practice, and, in case of anti-TNF secondary failure, a non-anti-TNF biologic is indicated. LLS is observed in anti-TNF receivers and, in most cases, resolves without anti-TNF withdrawal. A non-anti-TNF biologic is advisable in patients experiencing LLS. Non-anti-TNFs demonstrated a low or absent infection risk and are preferable in patients with comorbidities. Due to their positive effects on bone mass, anti-TNFs are indicated in women at osteoporosis risk, whereas non-anti-TNF have been poorly investigated. The emerging evidence of the relationship between RA and PD and the effects on anti-TNF efficacy should lead clinicians to consider the periodontal status in RA patients. Anti-TNFs may exert a positive effect on fertility and sexuality, and clinicians should explore these aspects in RA patients.ConclusionThe optimization of biologic therapies by taking into proper account the above issues would improve patient outcomes.

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Expert recommendations on the psychological needs of patients with rheumatoid arthritis

et al. 2018

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Prevalência de disfunção sexual entre pacientes acompanhadas na coorte Brasília de artrite reumatoide inicial

Abstract: The prevalence of sexual dysfunction found in this study was higher than that reported in the literature in healthy women. A knowledge of the extent of the problem is needed to provide adequate therapeutic options for these patients.

Cited by 16 publications

References 26 publications

Factors associated with sexual dysfunction in Taiwanese females with rheumatoid arthritis

Factors associated with sexual dysfunction in Taiwanese females with rheumatoid arthritis

Personalization of biologic therapy in patients with rheumatoid arthritis: less frequently accounted choice-driving variables

Expert recommendations on the psychological needs of patients with rheumatoid arthritis

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