Prevalence Trends in Chlamydial Infections Among Young Women Entering the National Job Training Program, 1998–2004

Joesoef, M R; Mosure, Debra J.

doi:10.1097/01.olq.0000204516.38760.9c

Cited by 18 publications

(5 citation statements)

References 29 publications

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“…Among females, Asians were less likely and whites more likely to have a diagnosed STI than African Americans. While the finding regarding Asian adolescents is in line with previous research, 30 the finding regarding African American youth stands in contrast to recent research suggesting relatively higher prevalence of STIs 29,35,39,40 …”

Section: Discussionmentioning

confidence: 99%

Sexually Transmitted Infection Among Adolescents Receiving Special Education Services

Mandell

Eleey

Cederbaum

et al. 2008

Journal of School Health

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BACKGROUND To estimate the relative risk of sexually transmitted infections (STIs) among children identified as having learning disabilities through the special education system. METHODS This cross-sectional study used special education data and Medicaid data from Philadelphia, Pennsylvania, for calendar year 2002. The sample comprised 51,234 Medicaid-eligible children, aged 12–17 years, 8015 of whom were receiving special education services. Claims associated with diagnoses of STIs were abstracted, and logistic regression was used to estimate the odds of STI among children in different special education categories. RESULTS There were 3% of males and 5% of females who were treated for an STI through the Medicaid system in 2002. Among females, those in the mental retardation (MR) category were at greatest risk (6.9%) and those in the emotionally disturbed or “no special education” category at lowest risk (4.9% each). Among males, STIs were most prevalent among those classified as mentally gifted (6.7%) and lowest among those in the MR category (3.0%). In adjusted analyses, males with specific learning disabilities and females with MR or who were academically gifted were at excess risk for STIs. CONCLUSIONS The finding that children with learning disabilities are at similar or greater risk for contracting STIs as other youth suggests the need to further understand their risk behaviors and the potential need to develop prevention programs specific to their learning needs.

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Section: Discussionmentioning

confidence: 99%

Sexually Transmitted Infection Among Adolescents Receiving Special Education Services

Mandell

Eleey

Cederbaum

et al. 2008

Journal of School Health

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“…In 2004 929,462 C. trachomatis infections were reported to the Centers for Disease Control and Prevention, a 5.9% increase compared to 2003 (6). Ongoing surveillance of 16-to 24-year-old women entering the U.S. National Job Training Program shows recent stabilization of C. trachomatis prevalence at roughly 10% after previous declines (22). Recently, the rates of C. trachomatis infection in Canada have begun to rebound in spite of, or possibly because of, public health measures taken to control the infection (4).…”

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confidence: 99%

Chlamydia muridarumInfection Elicits a Beta Interferon Response in Murine Oviduct Epithelial Cells Dependent on Interferon Regulatory Factor 3 and TRIF

Derbigny¹,

Hong²,

Kerr³

et al. 2007

Infect Immun

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Chlamydia trachomatis is the most common sexually transmitted bacterial infection in the United States. Utilizing cloned murine oviduct epithelial cell lines, we previously identified Toll-like receptor 2 (TLR2) as the principal epithelial pattern recognition receptor (PRR) for infection-triggered release of the acute inflammatory cytokines interleukin-6 and granulocyte-macrophage colony-stimulating factor. The infected oviduct epithelial cell lines also secreted the immunomodulatory cytokine beta interferon (IFN-␤) in a largely MyD88-independent manner. Although TLR3 was the only IFN-␤ production-capable TLR expressed by the oviduct cell lines, we were not able to determine whether TLR3 was responsible for IFN-␤ production because the epithelial cells were unresponsive to the TLR3 ligand poly(I-C), and small interfering RNA (siRNA) techniques were ineffective at knocking down TLR3 expression. To further investigate the potential role of TLR3 in the infected epithelial cell secretion of IFN-␤, we examined the roles of its downstream signaling molecules TRIF and IFN regulatory factor 3 (IRF-3) using a dominant-negative TRIF molecule and siRNA specific for TRIF and IRF-3. Antagonism of either IRF-3 or TRIF signaling significantly decreased IFN-␤ production. These data implicate TLR3, or an unknown PRR utilizing TRIF, as the source of IFN-␤ production by Chlamydia-infected oviduct epithelial cells.

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“…We also used robust methods to account for measurement error due to changing screening tests. In previous trend estimates, measurement error was addressed by adjusting for screening tests in generalized linear models or restricting by test type (9,10). These methods do not properly account for test sensitivities and specificities (20).…”

Section: Discussionmentioning

confidence: 99%

Chlamydia Prevalence Trends Among Women and Men Entering the National Job Training Program From 1990 Through 2012

Learner¹,

Torrone

Fine

et al. 2018

Sexual Trans Dis

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Prevalence Trends in Chlamydial Infections Among Young Women Entering the National Job Training Program, 1998–2004

Abstract: Among disadvantaged women aged 16 to 24 years entering a national job training program, the chlamydia prevalence and racial disparities in prevalence were consistently high from 1998 to 2004, especially among younger black women.

Cited by 18 publications

References 29 publications

Sexually Transmitted Infection Among Adolescents Receiving Special Education Services

Sexually Transmitted Infection Among Adolescents Receiving Special Education Services

Chlamydia muridarumInfection Elicits a Beta Interferon Response in Murine Oviduct Epithelial Cells Dependent on Interferon Regulatory Factor 3 and TRIF

Chlamydia Prevalence Trends Among Women and Men Entering the National Job Training Program From 1990 Through 2012

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