Prevalence, risk factors and pregnancy outcomes of women with vascular brain lesions in pregnancy

Maor, Gil Shechter; Faden, Majed S.; Brown, Richard N.

doi:10.1007/s00404-020-05451-3

Cited by 10 publications

(7 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Compared with other published cohorts we found substantially higher rates of vaginal delivery. Data from a contemporary North American study of 214 women with cerebral vascular malformations reported a caesarean section rate of 79% 8 …”

Section: Discussionmentioning

confidence: 99%

“…Data from a contemporary North American study of 214 women with cerebral vascular malformations reported a caesarean section rate of 79%. 8 We hypothesise that our vaginal delivery rate is higher because of detailed multidisciplinary care whereby women are provided with consistent information throughout their antenatal care and reassured about the safety of vaginal birth in the absence of prior cerebral haemorrhage.…”

Section: Discussionmentioning

confidence: 99%

“…6 Despite reassuring data on the safety of labour, and the American Heart Association guidance backed up by a recent review, 7 almost 80% of women in the USA with CVMs have a caesarean section. 8 We therefore sought to collect additional data on pregnancy safety and complications in the UK, where the caesarean section rate is generally much lower.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, the Valsalva manoeuvre, which is required in the active second stage of labour, does not appear to increase intracerebral venous pressure 6 . Despite reassuring data on the safety of labour, and the American Heart Association guidance backed up by a recent review, 7 almost 80% of women in the USA with CVMs have a caesarean section 8 …”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Maternal and fetal outcomes in women with cerebrovascular malformations in pregnancy: A multicentre retrospective cohort study

Cauldwell

Bredaki²,

Dassan

et al. 2021

BJOG

View full text Add to dashboard Cite

Objective: To determine maternal, obstetric and neonatal outcomes in a cohort of women with cerebrovascular malformations (CVMs) that include arterial venous malformations (AVMs) and cavernomas.Design: Retrospective cohort study.Setting: Six specialist centres managing pregnant women with neurological disorders.Population: Sixty-three women with CVMs in 83 pregnancies of ≥20 completed weeks' gestation. Methods: Retrospective case notes review.Main outcome measures: Neurological outcomes including rates of acute cerebral bleeding in pregnancy and reported seizures during pregnancy. Maternal outcomes included number of women with a livebirth and the proportion of women being delivered by caesarean section. Results: Most women had a good pregnancy outcome with high rates of vaginal delivery (73%) at term. There were no maternal deaths. Six women had an acute cerebral bleed, all of whom were delivered by planned caesarean section. In total, ten women had seizures in pregnancy (of whom four also had a bleed). Six (7%) babies were admitted to a neonatal unit. There was no significant difference in outcomes between women with AVMs and those with cavernomas. Conclusion:In the majority of cases, pregnancy outcomes were favourable, with most women having a vaginal delivery. All cases of cerebral bleeds that occurred were at a remove from the peripartum period.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Maternal and fetal outcomes in women with cerebrovascular malformations in pregnancy: A multicentre retrospective cohort study

Cauldwell

Bredaki²,

Dassan

et al. 2021

BJOG

View full text Add to dashboard Cite

show abstract

“…Diabetes and hypertension patients have relatively complicated vascular lesions and unstable endothelial function [13]. Therefore, during PCI treatment, coronary intimal tear or dissection is more likely to occur, which promotes platelet adhesion [14]. Besides, glucose can also directly damage coronary endothelial cells, these factors increase the incidence of ISR [15].…”

Section: Discussionmentioning

confidence: 99%

The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do

Wang

Qiao

Wang

et al. 2020

BMC Cardiovasc Disord

View full text Add to dashboard Cite

Background Percutaneous coronary intervention (PCI) is a common treatment for patients with coronary heart disease, and intra-stent restenosis (ISR) is a serious complication after PCI. It’s necessary to identify the potential risk factors to provide evidence for the prevention of ISR. Methods The patients who underwent coronary angiography 1 year after PCI in our hospital from January 2017 to May 2019 were selected. The characteristics and results of clinical examination of ISR and no-ISR patients were compared, Multivariate logistic regression analyses were performed to identify the risk factors. Results A total of 209 patients were included, the incidence of ISR after PCI was 30.62%. There were significant differences on the hypertension, diabetes, number of coronary artery lesions, reasons for stent implantation, the diameter of stent, the length of stent and stent position between ISR group and no-ISR patients (all p < 0.05). The LDL-C in ISR groups was significantly higher than that of no-ISR group (p = 0.048), there were no significant differences between two groups in FPG, TG, TC, HDL-C, Apo A1, Apo B, LP-a and glycated haemoglobin (all p > 0.05). The hypertension (OR 4.30, 95% CI 1.12–9.34), diabetes (OR 5.29, 95% CI 1.25–9.01), number of coronary artery lesions ≥ 2 (OR 4.84, 95% CI 1.21–9.55), LDL-C ≥ 1.9 mmol/L (OR 5.93, 95% CI 2.29–10.01), unstable angina (OR 2.92, 95% CI 1.20–4.55), left anterior descending artery (OR 4.01, 95% CI 1.73–7.58), diameter of stent ≥ 3 mm (OR 5.42, 95% CI 1.24–10.84), the length of stent > 20 mm (OR 3.06, 95% CI 1.19–5.22) were the independent risk factor for ISR (all p < 0.05). Conclusion It is necessary to take preventive measures against these risk factors to reduce ISR, and studies with larger sample size and longer follow-up on this issue are needed in the future.

show abstract

Mode of Delivery in Pregnant Women with Neurological Disorders

Fields,

Rosen

2023

Neurological Disorders in Pregnancy

View full text Add to dashboard Cite

Prevalence, risk factors and pregnancy outcomes of women with vascular brain lesions in pregnancy

Cited by 10 publications

References 30 publications

Maternal and fetal outcomes in women with cerebrovascular malformations in pregnancy: A multicentre retrospective cohort study

Maternal and fetal outcomes in women with cerebrovascular malformations in pregnancy: A multicentre retrospective cohort study

The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do

Mode of Delivery in Pregnant Women with Neurological Disorders

Contact Info

Product

Resources

About