Prevalence, Predictors, and Outcomes of Resistant Hypertension in Egyptian Population

Abstract

Background: Hypertension is a leading problem; it affects around thirty million adult Egyptians, according to the last national registry. The exact prevalence of resistant hypertension (RH) in Egypt wasn't spotted before. The purpose of this study was to determine the prevalence, predictors, and impact on adverse cardiovascular outcomes among adult Egyptians with RH. Methods:The present study examined a cohort of 990 hypertensive patients who were divided into two groups based on their blood pressure control; group I (n = 842) patients who achieved blood pressure control and group II (n = 148) patients who met the RH definition criteria. All patients underwent a close follow-up for one year to evaluate the major cardiovascular events. Results:The prevalence of RH was 14.9%. The main predictors impacting the cardiovascular outcomes of RH were advanced age (≥65 years), the presence of chronic kidney diseases, a BMI ≥ 30 kg/m 2 , and NSAID use. After one year of followup, the RH group displayed noticeably higher rates of major cardiovascular events, including new-onset atrial fibrillation (6.8% vs. 2.5%, P = 0.006), cerebral stroke (4.1% vs. 1.2%, P = 0.011), myocardial infarction (4.7% vs. 1.3%, P = 0.004), and acute heart failure (4.7% vs. 1.8%, P = 0.025). Conclusion:The prevalence of RH in Egypt is moderately high. Patients with RH have a far higher risk of cardiovascular events than those whose blood pressure is within control.2 Khalfallah et al.

Evaluating an Innovative Technology-based Intervention in Reducing Predictive Stroke Risk and Raising Awareness among Stroke-Free Hypertensive Patients

“…Moreover, another meta-analysis published in 2023 suggested that more intensive blood pressure-lowering therapy might be associated with a reduced risk of recurrent stroke and major cardiovascular events (Hsu et al, 2023). Therefore, the intervention has the potential to prevent a large number of stroke events and save lives in Egypt, where hypertension is highly prevalent and poorly controlled and it affects around thirty million adult Egyptians, according to the last national registry (Khalfallah, et al, 2023). Another notable finding of the study is the significant improvement in the glycemic control of the study group, as indicated by the remarkable reduction in the percentage of individuals with high haemoglobin A1c (≥6.5%) from 68.6% at pre-intervention to 14.7% at post-intervention as a follow-up, compared to a minimal reduction in the control group from 66.7% to 62.7%.…”