Prevalence pattern of MRSA from a rural medical college of North India

Abstract

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) has become a global challenge. The shift of this organism form hospital settings to community setting and increasing resistance to non-β-lactams antibiotics have further aggravated the crisis. This trend in MRSA has necessitated the knowledge and sensitization about this agent among physicians in rural and peripheral settings. Material and Methods: Present study was undertaken at Department of Microbiology at rural medical college of North India from January 2017 to December 2019 (3 years). All the clinical samples collected with aseptic precautions were processed as per standard protocol. All the Staphylococcus aureus isolates cultured were subjected to antimicrobial susceptibility testing as per CLSI guidelines 2019. Screening for MRSA was done by CLSI recommended methods, such as cefoxitin disc (30 μg), oxacillin disc (1 μg), and oxacillin screen agar as per CLSI recommendation. Results: A steady increase in number of MRSA isolates was observed from year 2017 to 2019 with overall prevalence being 33.7%. Most MRSA isolates were obtained from pus samples. Cefoxitin disc diffusion method is a dependable detection method compared to oxacillin disc diffusion and oxacillin screen agar for identification of MRSA. Conclusion: The rising trend of MRSA impresses upon the acute need of stringent infection control practices namely strict compliance to hand hygiene, prevention of misuse and overuse of antibiotics and a continuous surveillance program for MRSA. Also sensitization about this agent among the primary health physician is the need of hour to implement the control measures and limit its spread in communities.

Bacteriological profile and antibiogram analysis from a tertiary care centre in eastern India: Time to Act / ReAct

“…26,27 However, some of the authors have observed a lower prevalence of MRSA in their study but all of them reported increasing trend of MRSA prevalence in their study. 28,29 Our study found significantly higher prevalence of Inducible…”

Antibiotic susceptibility trends in bacterial isolates from wound infections

“…According to a multicentric study conducted in India, the prevalence of MRSA was 41% in 2013 [19]. In another study from North India, this figure reached 33.7% between 2017 and 2019 [20]. According to the Indian Council of Medical Research (ICMR) report on antimicrobial resistance, the prevalence of MRSA in India was 38.6% in 2018 and 42.1% in 2019 [21].…”

Spectrum of Virulence Factors in Clinical Isolates of Staphylococcus aureus and Prevalence of SCCmec Types in Methicillin-Resistant Staphylococcus aureus in a Tertiary Care Center

“… 24 A study conducted in North India over a period of 3 years reported that MRSA increased from 28% in 2017 to 35.1% in 2019 with overall prevalence being 33.7%. 25 The prevalence of MRSA infection was 37.34% according to a recent meta-analysis report from South India. 26 In Asia-Pacific region, MRSA accounts for up to 50% of Staphylococcus aureus bloodstream infections.…”