Prevalence of vitamin D status and its association with overweight or obesity in a population of Colombian children and adolescents

Rojas, Lyda Z.; Quintero-Lesmes, Doris Cristina; Gamboa-Delgado, Edna Magaly; Guío, Elizabeth; Serrano, Norma C.

doi:10.1017/jns.2020.47

Cited by 3 publications

(2 citation statements)

References 24 publications

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“…In African American adolescents with obesity, a correlation of low values of serum 25(OH) D with adiponectin, BMI, insulin resistance was observed [16]. Similar conclusions (connection of vitamin D deficiency with obesity markers) have been demonstrated among children living in the Caucasus, in tropical conditions (Malaysia, Colombia), Brazil [17][18][19][20].…”

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confidence: 72%

The Role of Obesit Y in the De Velopment of Vitamin D Deficiency Rickets in Children

Puhach

Kolesnyk

Herasymova

et al. 2021

PEP

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Vitamin D deficiency rickets is one of the most common diseases among children of the first years of life in many countries around the world. It is very important to understand the aforementioned nosological unit as a metabolism disorder, and not just as a D-deficiency state. In modern conditions, the risk factors for vitamin D deficiency rickets have undergone further study. The results of the research indicate that obesity is one of the risk factors for vitamin D deficiency in children. Thus, vitamin D metabolism, deposition, bioavailability and its biological role are dependent on the size of adipose tissue. The pathogenetic interaction between obesity andМvitamin D deficiency is probably predetermined by several mechanisms. Firstly, in case of obesity, vitamin D,Мwhich is a fat-soluble substance, is distributed in a considerable amount of adipose tissue, which leads toa decrease in its concentration in the blood plasma. Secondly, with excessive body weight there is a limitation of vitamin D bioavailability, caused by vitamin D capture with adipocytes and depositing in adipose tissue.Thirdly, there is a genetic proof that the increase in BMI leads to a decrease in vitamin D levels in blood serum.Recent studies have shown that adipose tissue may be the direct target of vitamin D physiological actions.It has been proved that vitamin D can affect obesity through numerous mechanisms, including protein expression, oxidative stress, inflammation and cellular metabolism. Currently, recommendations for treatment and prevention of vitamin D deficiency can be found in international foreign guidebooks whose authors state that obese children need a higher dosage of vitamin D compared to those whose physical development is consistent with age. Understanding the influence of adipose mass on bone tissue during its growth and development is a very important aspect for further health and pharmacotherapy strategies to prevent bone disorders.

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supporting

confidence: 72%

The Role of Obesit Y in the De Velopment of Vitamin D Deficiency Rickets in Children

Puhach

Kolesnyk

Herasymova

et al. 2021

PEP

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“…Increased obesity in children and adolescents is associated with vitamin D deficiency ( 43 ). Children with insufficient vitamin D intake (daily intake <70 IU) have higher body weight, BMI, waist circumference, and waist-to-hip ( 44 ). Contrary to other findings, adolescents showed the same relationship, but the concentration of parathyroid hormone did not increase ( 45 ).…”

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confidence: 99%

Associations Between Different Dietary Vitamins and the Risk of Obesity in Children and Adolescents: A Machine Learning Approach

Tang

Zhan²,

Wei³

et al. 2022

Front. Endocrinol.

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BackgroundsSimultaneous dietary intake of vitamins is considered as a common and real scenario in daily life. However, limited prospective studies have evaluated the association between multivitamins intake and obesity in children and adolescents.ObjectivesThis study aimed to evaluate the relationship between the intake of different dietary vitamins and the risk of obesity in children (6-11 years) and adolescents (12-19 years).MethodsWe conducted a cross-sectional study based on data from U.S. National Health and Nutrition Examination Survey, 2013-2016. A total of 3634 children and adolescents were included who had available data on dietary vitamins, obesity and covariates. We analyzed the dietary intake levels of nine vitamins, including vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin E, vitamin K. Multivariate logistic regression was used to model the associations between vitamins and obesity. Bayesian kernel machine regression (BKMR) was employed to explore the joint and independent effects of vitamins on obesity among children and adolescents.ResultsIn the multivariate logistic regression model, five vitamins (vitamin A, vitamin B1, vitamin B2, vitamin B12, and vitamin D) were negatively associated with obesity in children and adolescents. BKMR analysis showed that when the concentration of the nine vitamins was at or above the 55th percentile compared with the median value, the combined intake of these vitamins could significantly reduce the risk of obesity in children and adolescents. Potential interactions between vitamin B2 and vitamin B12 in increasing the risk of obesity in children and adolescents were observed.ConclusionsWe determine the combined effects of multivitamins on obesity in children and adolescents, and observe a significant interaction between vitamin B2 and vitamin B12. Further cohort studies are needed to clarify the health effects of multivitamins intake in a larger population.

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Vitamin D Status for Chinese Children and Adolescents in CNNHS 2016–2017

Jiang

et al. 2022

Nutrients

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Vitamin D is very important in maintaining children’s bone health because of its regulatory role in calcium and phosphate metabolism. To better understand vitamin D status and related risk factors of children and adolescents in China, this study analyzed the 25-hydroxyvitamin-D (25(OH)D) concentration of children and adolescents aged 6–17 years in China and assessed the risk factors of vitamin D deficiency and insufficiency. We analyzed the data of 25(OH)D concentration collected from the China National Nutrition and Health Survey of Children and Lactating Mothers in 2016–2017 (CNNHS 2016–2017). The age, sex, region type, ethnicities, season, weight and height were recorded, measured by unified questionnaire, equipment and standards. The concentration of 25(OH)D was detected by LC-MS/MS. A total of 64,391 participants from the cross-sectional study of CNNHS in 2016–2017 were included in this study. The median serum 25(OH)D concentration was 17.70 (13.20–22.68) ng/mL, 18.70 (14.10–23.80) ng/mL in boys and 16.60 (12.40–21.40) ng/mL in girls. The total prevalence rate of vitamin D deficiency and insufficiency was 65.98% when the cut-off was 20 ng/mL, 60.42% for boys and 71.99% for girls. According to the results of logistic regression analysis, girls aged above 12 y, living in midlands and northern regions, in spring and winter seasons and with abdominal obesity will have a significantly increased risk of vitamin D deficiency and insufficiency among Chinese children and adolescents. The results showed that vitamin D deficiency and insufficiency are very common among children and adolescents aged 6–17 y in China. They should be encouraged to have more effective sunlight exposure, increased intake of vitamin D from food or supplements in their diet, especially for those aged above 12 y, living in the northern or midlands areas, in spring and winter, and abdominally obese.

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Prevalence of vitamin D status and its association with overweight or obesity in a population of Colombian children and adolescents

Cited by 3 publications

References 24 publications

The Role of Obesit Y in the De Velopment of Vitamin D Deficiency Rickets in Children

The Role of Obesit Y in the De Velopment of Vitamin D Deficiency Rickets in Children

Associations Between Different Dietary Vitamins and the Risk of Obesity in Children and Adolescents: A Machine Learning Approach

Vitamin D Status for Chinese Children and Adolescents in CNNHS 2016–2017

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